Naxo 500 mg (Tablet)
Unit Price: ৳ 8.03 (5 x 10: ৳ 401.50)
Strip Price: ৳ 80.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Navana pharmaceuticals ltd |
| Also available as |
Indications
- relief of rheumatoid arthritis
- relief of osteoarthritis
- relief of ankylosing spondylitis
- relief of juvenile arthritis
- relief of tendonitis
- relief of bursitis
- relief of acute gout
- management of primary dysmenorrhea & pain
Pharmacology
- blocks COX-1 and COX-2 enzymes
- decreased prostaglandin synthesis
- antipyretic properties
- analgesic properties
- anti-inflammatory properties
- unique functional differences of COX-1 and COX-2 enzymes
Dosage & Administration
- should be taken with water
- oral preparations
- enteric coated tablet dosage for adults
- enteric coated tablet dosage for children
- suspension dosage for children
- gel application frequency
Interaction
- diminishes antihypertensive effect of ACE inhibitors
- delays the absorption of Naxo with antacids & sucralfate
- increases adverse effects with aspirin
- reduces the natriuretic effect of diuretics
- enhances the toxicity of methotrexate
- increases the risk of GI bleeding with warfarin
- increases the risk of GI bleeding with SSRIs
Contraindications
- known hypersensitivity to Naproxen
- asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- gastrointestinal side effects
- central nervous system side effects
- dermatological side effects
- cardiovascular side effects
- other reported side effects
Pregnancy & Lactation
- adverse effects on the fetus
- delay in parturition
- premature closure of the ductus arteriosus
- severe pulmonary hypertension in infants
- excretion in breast milk
- careful balancing of benefits and risks
Precautions & Warnings
- renal effects
- hepatic effects
- abnormal renal pathology
- acute interstitial nephritis
- hematuria
- proteinuria
- nephrotic syndrome
- monitoring of serum creatinine and/or creatinine clearance
- caution in patients with significantly impaired renal function
- accumulation of naproxen metabolites
- moderate to severe jaundice
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- temperature below 30°C
- protected from light & moisture
- keep out of reach of children