Nuprafen 500 mg (Tablet)
Unit Price: ৳ 7.85 (5 x 10: ৳ 392.50)
Strip Price: ৳ 78.50
Medicine Details
Category | Details |
---|---|
Generic | Naproxen sodium |
Company | Beximco pharmaceuticals ltd |
Also available as |
Indications
- rheumatoid arthritis
- osteoarthritis
- ankylosing spondylitis
- juvenile arthritis
- tendonitis
- bursitis
- acute gout
- dysmenorrhea
Pharmacology
- blockage of COX-1 and COX-2 enzymes
- decreased prostaglandin synthesis
- antipyretic properties
- analgesic properties
- anti-inflammatory properties
- unique functional differences of COX-1 and COX-2 enzymes
Dosage & Administration
- oral preparation
- taken with water
- preference after meals
- different dosages for different indications
- enteric coated tablets
- suspension for children
- gel for topical application
Interactions
- ACE inhibitors
- Antacids & Sucralfate
- Aspirin
- Diuretics
- Methotrexate
- Warfarin
- Selective Serotonin Reuptake Inhibitors (SSRI)
Contraindications
- known hypersensitivity to Naproxen
- asthma
- urticaria
- allergic-type reactions after taking aspirin or other NSAIDs
- perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal symptoms
- Central Nervous System symptoms
- Dermatological symptoms
- Cardiovascular symptoms
- Other reported symptoms
Pregnancy & Lactation
- adverse effect on the fetus
- delay in parturition
- premature closure of the ductus arteriosus
- severe pulmonary hypertension in infants
- excretion in breast milk
- balance of benefits and risks
Precautions & Warnings
- Renal effects
- Hepatic effects
- renal pathology
- acute interstitial nephritis
- hematuria
- proteinuria
- nephrotic syndrome
- accumulation of naproxen metabolites
- serum creatinine monitoring
- creatinine clearance monitoring
- impaired renal function
- hepatotoxicity
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- temperature below 30°C
- protected from light
- protected from moisture
- keep out of the reach of children