Nupralgin 250 mg (Tablet)

Unit Price: ৳ 5.00 (12 x 4: ৳ 240.00)
Strip Price: ৳ 20.00

Medicine Details

Category Details
Generic Naproxen sodium
Company Ibn sina pharmaceuticals ltd
Also available as
Nupralgin 500 mg tablet

Product Title

  • Nupralgin

Categories

  • Pain Relief
  • Anti-inflammatory
  • Analgesic
  • NSAID

Description

  • Indications:
    • Relief of rheumatoid arthritis symptoms
    • Relief of osteoarthritis symptoms
    • Relief of ankylosing spondylitis symptoms
    • Relief of juvenile arthritis symptoms
    • Relief of tendonitis symptoms
    • Relief of bursitis symptoms
    • Relief of acute gout symptoms
    • Management of primary dysmenorrhea & pain
  • Pharmacology:
    • Blocks COX-1 and COX-2 enzymes
    • Decreases prostaglandin synthesis
  • Dosage & Administration:
    • Naproxen Enteric Coated Tablet Adult:
      • For rheumatoid arthritis/osteaoarthritis/ankylosing spondylitis: 500-1000mg per day
      • For acute gout: 750mg initially, then 250mg every 8 hours
      • For dysmenorrhoea: 500mg initially, followed by 250mg at 6-8 hour intervals
      • For other indications like analgesia and acute musculoskeletal disorders: 500mg initially, followed by 250mg at 6-8 hour intervals
    • Naproxen Suspension Children: 10 mg/kg/day for juvenile rheumatoid arthritis
  • Interaction:
    • ACE inhibitors diminish antihypertensive effect
    • Antacids & Sucralfate delay absorption
    • Aspirin increases adverse effects
    • Diuretics reduce natriuretic effect
    • Methotrexate enhances toxicity
    • Warfarin increases risk of GI bleeding
    • Selective Serotonin Reuptake Inhibitors increase risk of GI bleeding
  • Contraindications:
    • Known hypersensitivity to Naproxen
    • Patients with asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
    • Treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
  • Side Effects:
    • Gastrointestinal: heartburn, abdominal pain, nausea, diarrhea, dyspepsia
    • Central Nervous System: headache, vertigo, drowsiness
    • Dermatological: pruritus, purpura
    • Cardiovascular: edema, palpitation
    • Others: visual disturbances, hearing disturbances
  • Pregnancy & Lactation:
    • May have adverse effects on fetus
    • Causes a delay in parturition in animals
    • Associated with premature closure of ductus arteriosus and severe pulmonary hypertension in infants
    • Excreted in small amounts in breast milk
  • Precautions & Warnings:
    • Renal effects: potential renal pathology, caution in patients with significantly impaired renal function
    • Hepatic effects: reports of moderate to severe jaundice
  • Therapeutic Class:
    • Drugs for Osteoarthritis
    • Drugs used for Rheumatoid Arthritis
    • Non-steroidal Anti-inflammatory Drugs (NSAIDs)
  • Storage Conditions: Keep below 30°C, protected from light & moisture, keep out of reach of children

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