Servinaprox 250 mg (Tablet)
Unit Price: ৳ 7.00 (5 x 10: ৳ 350.00)
Strip Price: ৳ 70.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Sandoz a novartis division |
| Also available as |
Indications
- Relief of rheumatoid arthritis symptoms
- Relief of osteoarthritis symptoms
- Relief of ankylosing spondylitis symptoms
- Relief of juvenile arthritis symptoms
- Relief of tendonitis symptoms
- Relief of bursitis symptoms
- Relief of acute gout symptoms
- Management of primary dysmenorrhea & pain
Pharmacology
- Blocks COX-1 and COX-2 enzymes
- Decreases prostaglandin synthesis
- Mediates antipyretic, analgesic and anti-inflammatory properties
- May cause gastrointestinal upset and renal toxicities
Dosage & Administration
- Oral administration with water
- Different dosages for adults and children
- Enteric Coated Tablet and Suspension forms available
- Gel for topical application
Interaction
- Diminishes antihypertensive effect of ACE inhibitors
- Delays absorption with antacids & Sucralfate
- Increases adverse effects with Aspirin
- Reduces natriuretic effect of Diuretics
- Enhances toxicity of Methotrexate
- Increases risk of GI bleeding with Warfarin
- Increases risk of GI bleeding with Selective Serotonin Reuptake Inhibitors (SSRI)
Contraindications
- Known hypersensitivity to Naproxen
- Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
- Perioperative pain in the setting of coronary artery bypass graft (CABG) surgery
Side Effects
- Gastrointestinal side effects
- Central Nervous System side effects
- Dermatological side effects
- Cardiovascular side effects
- Other side effects like visual and hearing disturbances
Pregnancy & Lactation
- May have adverse effect on the fetus
- Causes delay in parturition
- Excreted in small amounts in breast milk
- Requires careful balancing of benefits and risks during pregnancy
- Considerations for nursing mothers
Precautions & Warnings
- Possible renal effects
- Reports of acute interstitial nephritis and abnormal renal pathology
- Eliminated primarily by the kidneys
- Caution in patients with impaired renal function
- Monitoring of serum creatinine and/or creatinine clearance advised
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store below 30°C temperature
- Protect from light & moisture
- Keep out of the reach of children