Nevan TS 0.3% (Ophthalmic Suspension)

Indications

• Treatment of post-operative ocular pain and inflammation including cataract surgery
• Inhibition of surgery induced miosis
• Prevention of post-operative cystoid macular edema (CME)

Pharmacology

• Nepafenac is a nonsteroidal anti-inflammatory prodrug (NSAID)
• Converted to Amfenac, a potent nonsteroidal anti-inflammatory drug
• Thought to inhibit the action of cyclooxygenase enzyme

Dosage & Administration

• Instill 1 drop 3 times daily 1 day prior to cataract surgery and continued on the day of surgery and through the first 2 weeks of the post-operative period
• Instill 1 drop 3 times daily 1 day before surgery & on the day of surgery for surgery induced miosis
• Instill 1 drop 3 times daily 1 day before surgery and continued on the day of surgery and through the first 6 weeks of the post-operative period for prevention of post-operative CME
• Instill 1 drop once daily 1 day prior to cataract surgery and continued on the day of surgery and through the first 2 weeks of the post-operative period for 0.3% suspension
• An additional drop should be administered 30 to 120 minutes prior to surgery for 0.3% suspension

Contraindications

• Hypersensitivity to any of the ingredients in the formulation

Side Effects

• Foreign body sensation
• Lid margin crusting
• Ocular discomfort
• Ocular hyperemia

Pregnancy & Lactation

• Use in pregnancy only if potential benefit justifies potential risk to the fetus
• Caution when administered to a nursing mother

Precautions & Warnings

• Use with caution in patients with known bleeding tendencies or who are receiving medications which may prolong bleeding time

Use in Special Populations

• Safety and effectiveness in children below 18 years of age not established
• No overall differences in safety or effectiveness observed between elderly and younger patients

Therapeutic Class

• Ophthalmic Non-Steroid drugs

Related Brands

• Nevan 0.1% (Ophthalmic Suspension) - aristopharma-ltd