Ecless 10% w/w (Gel)

15 gm tube: ৳ 60.00

Medicine Details

Indications

  • rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • juvenile arthritis
  • tendonitis
  • bursitis
  • acute gout
  • primary dysmenorrhea
  • pain relief

Pharmacology

  • blocks COX-1 and COX-2 enzymes
  • decreases prostaglandin synthesis
  • antipyretic properties
  • analgesic properties
  • anti-inflammatory properties

Dosage & Administration

  • oral administration
  • should be taken with water
  • preferably after meals
  • adult dosage recommendations
  • children dosage recommendations
  • enteric-coated tablet dosage
  • oral suspension dosage
  • gel application instructions

Interaction

  • diminishes antihypertensive effect of ACE inhibitors
  • delays absorption with antacids & sucralfate
  • increases adverse effects with aspirin
  • reduces natriuretic effect of diuretics
  • enhances methotrexate toxicity
  • increases risk of GI bleeding with warfarin
  • increases risk of GI bleeding with selective serotonin reuptake inhibitors (SSRI)

Contraindications

  • known hypersensitivity to naproxen
  • asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
  • perioperative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

  • gastrointestinal side effects
  • central nervous system side effects
  • dermatological side effects
  • cardiovascular side effects
  • other reported side effects

Pregnancy & Lactation

  • adverse effects on the fetus
  • delay in parturition
  • premature closure of the ductus arteriosus
  • severe pulmonary hypertension in infants
  • excretion in breast milk
  • possible risks to the fetus
  • safety during breastfeeding

Precautions & Warnings

  • renal effects
  • abnormal renal pathology
  • acute interstitial nephritis
  • hematuria
  • proteinuria
  • nephrotic syndrome
  • hepatic effects
  • jaundice
  • renal function monitoring
  • creatinine clearance monitoring

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • temperature
  • protected from light
  • protected from moisture
  • keep out of reach of children

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