Ultranax 500 mg (Tablet)

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)

Strip Price: ৳ 80.00

Medicine Details

Category	Details
Generic	Naproxen sodium
Company	Ad din pharmaceuticals ltd

Indications

rheumatoid arthritis
osteoarthritis
ankylosing spondylitis
juvenile arthritis
tendonitis
bursitis
acute gout
management of primary dysmenorrhea & pain

Pharmacology

Naproxen blocks COX-1 and COX-2 enzymes, leading to decreased prostaglandin synthesis. COX-2 enzyme mediates antipyretic, analgesic, and anti-inflammatory properties while COX-1 enzyme is linked to gastrointestinal upset and renal toxicities.

Dosage & Administration

Naproxen oral preparations should be taken with water preferably after meals.
Dosage varies for different conditions and age groups.

Interaction

ACE inhibitors diminish the antihypertensive effect
Antacids & Sucralfate delay absorption
Aspirin increases adverse effects
Diuretics reduce natriuretic effect
Methotrexate enhances toxicity
Warfarin increases risk of GI bleeding
Selective Serotonin Reuptake Inhibitors (SSRI) increase risk of GI bleeding

Contraindications

Hypersensitivity to Naproxen
Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
Treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

Gastrointestinal: heartburn, abdominal pain, nausea, diarrhea, dyspepsia
Central Nervous System: headache, vertigo, drowsiness
Dermatological: pruritus, purpura
Cardiovascular: edema, palpitation
Others: visual disturbances, hearing disturbances

Pregnancy & Lactation

Naproxen may have adverse effects on the fetus and excreted in small amounts in breast milk. Balancing the benefits to the mother against the possible risks to the fetus is required.

Precautions & Warnings

Renal effects: long-term administration may result in renal papillary necrosis and other abnormal renal pathology
Hepatic effects: few reports of moderate to severe jaundice attributed to Ultranax

Therapeutic Class

Drugs for Osteoarthritis
Drugs used for Rheumatoid Arthritis
Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Keep below 30°C temperature, protected from light & moisture, and out of the reach of children.