Zenosyn 500 mg (Tablet)

Unit Price: ৳ 7.02 (3 x 10: ৳ 210.60)
Strip Price: ৳ 70.20

Medicine Details

Category Details
Generic Naproxen sodium
Company Sharif pharmaceuticals ltd

Indications

  • Rheumatoid arthritis
  • Osteoarthritis
  • Ankylosing spondylitis
  • Juvenile arthritis
  • Tendonitis
  • Bursitis
  • Acute gout
  • Primary dysmenorrhea & pain

Pharmacology

  • Blocks COX-1 and COX-2 enzymes
  • Decreases prostaglandin synthesis
  • Unique functional differences between COX-1 and COX-2 enzymes

Dosage & Administration

  • Adult dosage for rheumatoid arthritis/osteoarthritis/ankylosing spondylitis
  • Adult dosage for acute gout
  • Adult dosage for dysmenorrhoea
  • Adult dosage for analgesia and acute musculoskeletal disorders
  • Children's dosage for juvenile rheumatoid arthritis
  • Naproxen Gel application instructions

Interaction

  • ACE inhibitors effect
  • Antacids and Sucralfate effect
  • Aspirin effect
  • Diuretics effect
  • Methotrexate interaction
  • Warfarin interaction
  • Selective Serotonin Reuptake Inhibitors (SSRI) interaction

Contraindications

  • Hypersensitivity to Naproxen
  • Asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs
  • Treatment of perioperative pain in the setting of coronary artery bypass graft (CABG) surgery

Side Effects

  • Gastrointestinal effects
  • Central Nervous System effects
  • Dermatological effects
  • Cardiovascular effects
  • Other reported effects

Pregnancy & Lactation

  • Adverse effects on the fetus
  • Delay in parturition
  • Premature closure of ductus arteriosus
  • Severe pulmonary hypertension in infants
  • Excretion in breast milk
  • Balancing benefits and risks

Precautions & Warnings

  • Renal effects
  • Hepatic effects
  • Reports of acute interstitial nephritis
  • Monitoring of serum creatinine and/or creatinine clearance
  • Caution in patients with impaired renal function

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Keep below 30°C
  • Protected from light & moisture
  • Keep out of the reach of children

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