Nax-N 250 mg (Tablet)
Unit Price: ৳ 4.00 (50's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Naproxen sodium |
| Company | Novus pharmaceuticals ltd |
| Also available as |
Indications
- Relief of rheumatoid arthritis symptoms
- Relief of osteoarthritis symptoms
- Relief of ankylosing spondylitis symptoms
- Relief of juvenile arthritis symptoms
- Relief of tendonitis symptoms
- Relief of bursitis symptoms
- Relief of acute gout symptoms
- Management of primary dysmenorrhea & pain
Pharmacology
- Blocks COX-1 and COX-2 enzymes
- Decreases prostaglandin synthesis
- Differentiates COX-1 and COX-2 functions
Dosage & Administration
- Taken with water, preferably after meals
- Adult dosage for different indications
- Children's dosage for specific conditions
- Application frequency for gel
Interaction
- Diminished antihypertensive effect with ACE inhibitors
- Delayed absorption with antacids & Sucralfate
- Increased adverse effects with Aspirin
- Reduced natriuretic effect with Diuretics
Contraindications
- Known hypersensitivity to Naproxen
- Asthma, urticaria, or allergic-type reactions to aspirin or other NSAIDs
- Treatment of perioperative pain in CABG surgery
Side Effects
- Gastrointestinal: Heartburn, abdominal pain, nausea, diarrhea, dyspepsia
- Central Nervous System: Headache, vertigo, drowsiness
- Dermatological: Pruritus (itching), purpura
- Cardiovascular: Edema, palpitation
- Others: Visual disturbances, hearing disturbances
Pregnancy & Lactation
- Adverse effect on fetus
- Delayed parturition in animals
- Premature closure of ductus arteriosus
- Severe pulmonary hypertension in infants
- Consideration of risks and benefits for first and third trimesters
- Excretion in breast milk
- Recommendation on breastfeeding during therapy
Precautions & Warnings
- Renal effects: Reports of abnormal renal pathology
- Recommended caution in impaired renal function
- Monitoring of serum creatinine and/or clearance
- Caution with creatinine clearance <20ml/min
- Hepatic effects: Reports of moderate to severe jaundice
Therapeutic Class
- Osteoarthritis drugs
- Rheumatoid arthritis drugs
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Temperature: Below 30°C
- Protection: From light & moisture
- Keep out of the reach of children