Naprotec 500 mg+20 mg (Tablet (Delayed Release))

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Naproxen sodium esomeprazole magnesium
Company Sharif pharmaceuticals ltd
Also available as
Naprotec 375 mg tablet

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Decrease risk of gastric ulcers

Pharmacology

  • Immediate release Esomeprazole Magnesium layer
  • Enteric-coated Naproxen core
  • Prostaglandin synthesis inhibition
  • Proton pump inhibitor

Dosage

  • Effective dose consideration
  • Administration for various conditions
  • Dosage for different patient weights

Administration

  • Tablet administration instructions

Interaction

  • Concomitant use of NSAIDs
  • Interference with drug absorption
  • Effect of high-fat food on absorption

Contraindications

  • Known hypersensitivity
  • History of allergic reactions
  • Use during peri-operative period

Side Effects

  • Decreased incidence of gastrointestinal side effects
  • Potential cardiovascular and cerebrovascular effects
  • Possible gastrointestinal bleeding
  • Gastric ulcers, perforation or GI bleeding

Pregnancy & Lactation

  • Use during pregnancy
  • Excretion in human milk
  • Impact on fertility

Precautions & Warnings

  • Avoidance of NSAID combination
  • Low dose acetylsalicylic acid use
  • Regular surveillance for long-term treatment
  • Increased risk in older people

Use in Special Populations

  • Elderly patients use caution
  • Not recommended for patients with renal impairment
  • Monitoring for hepatic insufficiency

Overdose Effects

  • Symptoms of Naproxen and Esomeprazole overdose
  • Management for NSAID overdose
  • General supportive measures for overdose

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Temperature and light/moisture protection

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