Naprox Plus 375 mg+20 mg (Tablet (Delayed Release))

Unit Price: ৳ 13.00 (5 x 6: ৳ 390.00)

Strip Price: ৳ 78.00

Medicine Details

Category	Details
Generic	Naproxen sodium esomeprazole magnesium
Company	Eskayef pharmaceuticals ltd
Also available as	Naprox plus 500 mg tablet

Relief of signs and symptoms of Osteoarthritis
Relief of signs and symptoms of Rheumatoid arthritis
Relief of signs and symptoms of Ankylosing spondylitis
Decrease the risk of developing gastric ulcers in patients at risk of developing NSAID-associated gastric ulcers

Use the lowest effective dose for the shortest duration
Adults dose: One tablet twice daily of either: 375 mg naproxen/20 mg of esomeprazole; or 500 mg naproxen/20 mg of esomeprazole
Juvenile Idiopathic Arthritis dose: Depends on weight

Concomitant use of NSAIDs may reduce the antihypertensive effect of ACE inhibitors, diuretics, and beta-blockers
Warfarin interaction may result in increased risk of a bleeding complication
Inhibits the absorption of drugs where gastric pH is an important determinant of bioavailability
Administration with high-fat food affects absorption of naproxen

Known hypersensitivity to any component of this tablet or substituted benzimidazoles
History of asthmay urticaria or other allergic-type reactions after taking aspirin or other NSAIDs
Use during the peri-operative period in the setting of coronary artery bypass graft (CABG) surgery

Decrease the occurrence of gastric ulcers and NSAID associated upper gastrointestinal adverse events
Increased risk of arterial thrombotic events
Gastrointestinal adverse events
Oedema, hypertension, and cardiac failure
Nausea, vomiting, diarrhea, flatulence, constipation, dyspepsia, abdominal pain
Peptic ulcers, perforation or GI bleeding
Gastritis
Exacerbation of colitis and Crohn's disease

Avoid combination with NSAIDs including cyclooxygenase-2 selective inhibitors
Use with low dose acetylsalicylic acid
Minimize undesirable effects by using the lowest effective dose
Risk-factors for developing NSAID related gastro-intestinal complications
Increased frequency of adverse reactions in older people
May exacerbate gastrointestinal disease
Caution in patients with a history of gastrointestinal disease
Appropriate monitoring for patients with a history of hypertension and/or mild to moderate congestive heart failure
Consideration for patients with risk factors for cardiovascular events
Monitor patients with hepatic and renal impairment closely

Naproxen unbound plasma fraction is increased in the elderly
Not recommended for use in patients with moderate to severe or severe renal impairment
Monitor patients with mild to moderate hepatic impairment closely
Not recommended in patients with severe hepatic impairment