Novoxen 375 mg+20 mg (Tablet (Delayed Release))

Unit Price: ৳ 11.00 (5 x 4: ৳ 220.00)

Strip Price: ৳ 44.00

Medicine Details

Category	Details
Generic	Naproxen sodium esomeprazole magnesium
Company	Orion pharma ltd
Also available as	Novoxen 500 mg tablet

Reduction of antihypertensive effect of ACE inhibitors, diuretics & beta-blockers
Increased risk of bleeding complication with concomitant use of warfarin
Interference with absorption of drugs like Ketoconazole, iron salts and digoxin
Effect of administration with high-fat food on absorption of naproxen

Known hypersensitivity to any component
History of asthmay urticaria or other allergic-type reactions after taking aspirin or other NSAIDs
Use during the peri-operative period in the setting of coronary artery bypass graft (CABG) surgery

Decrease in occurrence of gastric ulcers and NSAID associated upper gastrointestinal adverse events
Potential association with arterial thrombotic events
Gastrointestinal adverse events like peptic ulcers, perforation or GI bleeding
Other adverse events like oedema, hypertension, cardiac failure, naussea, vomiting, diarrhoea, dyspepsia, abdominal pain

Avoidance of combination with NSAIDs including cyclooxygenase-2 selective inhibitors
Minimization of undesirable effects by using lowest effective dose
Risk-factors for developing NSAID related gastro-intestinal complications
Increased frequency of adverse reactions in older people
Monitoring and advice required for patients with history of hypertension and/or mild to moderate congestive heart failure
Effects of long-term administration on renal papillary necrosis and other renal injury

Increased unbound plasma fraction of naproxen in elderly
Caution and possible dose reduction in elderly patients
Non-recommendation for use in patients with moderate to severe or severe renal impairment
Monitoring and dose reduction consideration based on hepatic insufficiency