Enar 375 mg+20 mg (Tablet (Delayed Release))

Unit Price: ৳ 12.00 (7 x 4: ৳ 336.00)
Strip Price: ৳ 48.00

Medicine Details

Category Details
Generic Naproxen sodium esomeprazole magnesium
Company Medicon pharmaceuticals ltd
Also available as
Enar 500 mg tablet

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Gastric ulcers risk reduction

Mode of action

  • Immediate release Esomeprazole Magnesium layer
  • Enteric-coated Naproxen core
  • Prostaglandin synthesis inhibition
  • Proton pump inhibitor mechanism

Dosage

  • Adult dosage
  • Juvenile idiopathic arthritis dosage
  • Different strengths combination
  • Twice daily administration

Administration

  • Do not split, chew, crush or dissolve the tablet
  • Recommended intake 30 minutes before meals

Interaction

  • NSAID interaction with ACE inhibitors, diuretics & beta-blockers
  • Interaction with warfarin
  • Gastric acid secretion inhibition
  • Effects with high-fat food

Contraindications

  • Hypersensitivity to components
  • Asthma or allergic-type reactions history
  • Use during coronary artery bypass graft surgery

Side effects

  • Decreased occurrence of gastric ulcers
  • Potential association with arterial thrombotic events
  • Gastrointestinal adverse events
  • Reported gastrointestinal effects

Pregnancy lactation

  • Contraindicated during third trimester
  • Excretion in human milk
  • Impairment of female fertility

Precautions warnings

  • Risk factors for NSAID related gastro-intestinal complications
  • Special precautions for older people
  • Recommendations for patients with gastrointestinal disease
  • Cardiovascular and cerebrovascular effects
  • Renal effects in long-term administration

Pediatric uses

  • Elderly patient usage caution
  • Not recommended for moderate to severe renal impairment
  • Close monitoring for hepatic insufficiency patients

Overdose effects

  • Symptoms of Naproxen and Esomeprazole overdose
  • Management guidelines for overdose

Drug classes

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • NSAIDs

Storage conditions

  • Store below 30°C
  • Protection from light and moisture
  • Keep out of reach of children

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