Nimovo 500 mg+20 mg (Tablet (Delayed Release))

Unit Price: ৳ 15.00 (4 x 10: ৳ 600.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Naproxen sodium esomeprazole magnesium
Company Nipro jmi pharma ltd

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Gastric ulcers risk reduction

Pharmacology

  • Immediate release Esomeprazole Magnesium layer
  • Enteric-coated Naproxen core
  • Prostaglandin synthesis inhibition
  • Proton pump inhibition
  • Reduction of gastric acidity

Dosage

  • Lowest effective dose
  • Shortest duration
  • Adult dosage options
  • Juvenile dosage options

Administration

  • Do not split, chew, crush, or dissolve tablet
  • Take at least 30 minutes before meals

Interaction

  • Reduction of antihypertensive effect
  • Increased risk of bleeding complication
  • Interference with drug absorption
  • Effect of high-fat food on absorption

Contraindications

  • Hypersensitivity to tablet components
  • History of allergic-type reactions
  • Use during peri-operative period

Side Effects

  • Decreased incidence of gastrointestinal side effects
  • Decreased occurrence of gastric ulcers
  • Risk of arterial thrombotic events
  • Gastrointestinal adverse events
  • Hypertension and cardiac failure
  • Gastrointestinal adverse events

Pregnancy & Lactation

  • Use during first and second trimester
  • Contradiction during third trimester
  • Excretion in human milk
  • Effect on fertility

Precautions & Warnings

  • Avoidance of NSAID combination
  • Use with low dose acetylsalicylic acid
  • Regular surveillance for long-term treatment patients
  • Increased frequency of adverse reactions in older people
  • Gastrointestinal bleeding risk factors
  • Monitoring and advice for hypertension/heart failure patients
  • Renal injury risk
  • Dosage adjustment for elderly and renal impairment patients
  • Hepatic insufficiency monitoring

Use in Special Populations

  • Plasma concentration changes in elderly
  • Contraindication for severe renal impairment
  • Closely monitoring patients with hepatic impairment

Overdose Effects

  • Symptoms of Naproxen overdose
  • Symptoms of esomeprazole overdose
  • Symptomatic and supportive care for NSAID overdose
  • Symptomatic and general supportive measures for esomeprazole overdose

Therapeutic Class

  • Osteoarthritis drug
  • Rheumatoid arthritis drug
  • NSAID

Storage Conditions

  • Temperature and light protection
  • Keep out of reach of children

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