Enocam 20 mg (Tablet)
Unit Price: ৳ 8.03 (3 x 10: ৳ 240.90)
Strip Price: ৳ 80.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Tenoxicam |
| Company | Acme laboratories ltd |
Indications
- Rheumatoid arthritis
- Osteoarthritis
- Arthrosis
- Ankylosing spondylitis
- Tendinitis
- Bursitis
- Periarthritis
- Acute gout
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Anti-inflammatory properties
- Analgesic properties
- Antipyretic properties
- Platelet aggregation inhibition
- Prostaglandin biosynthesis inhibition
- Metalloproteinases inhibition
Dosage
- Standard dosage of 20 mg daily
- Acute gout dosage of 40 mg for two days followed by 20 mg for five days
- Early therapeutic effect
- Progressive increase in response
- Avoid daily doses higher than 20 mg for chronic disorders
- Reduction to a daily oral dose of 10 mg for maintenance
Administration
- Tablets to be taken with water
- Preferable to take with or immediately after a meal
Interaction
- Displacement from protein-binding sites by salicylate
- Concurrent treatment with salicylate
- Reduced renal tubular secretion of methotrexate
- Concurrent administration with gold, penicillamine, or probenecid
- Decreased renal clearance of lithium
- Attenuation of antihypertensive effects
- Interaction with furosemide
- Attenuation of antihypertensive effects of alpha-adrenergic blockers and ACE-inhibitors
- No interaction with centrally-acting alpha agonists or calcium channel blockers
- No interaction with atenolol
- Concurrent dosing with digitalis products
- No interaction with antacids, cimetidine, warfarin, phenprocoumon, oral antidiabetic drugs, or low molecular weight heparin
Contraindications
- Hypersensitivity to the drug
- Induction of symptoms of asthma, rhinitis, or urticaria by salicylates or other NSAIDs
- Upper gastrointestinal tract diseases
Side Effects
- Gastric, epigastric, and abdominal discomfort
- Dyspepsia
- Heartburn
- Nausea
- Dizziness
- Headache
- Constipation
- Diarrhea
- Stomatitis
- Gastritis
- Vomiting
- Ulcers
- Gl-bleeding
- Fatigue
- Sleep disturbances
- Appetite loss
- Dry mouth
- Vertigo
- Itching
- Erythema
- Exanthema
- Rash
- Urticaria
- Increase in BUN or creatinine
- Edema
- Increased liver enzyme activity
- Palpitations
- Visual disturbances
- Stevens-Johnson and Lyell's syndrome
- Photosensitivity reaction
- Vasculitis
- Anemia
- Agranulocytosis
- Leukopenia
- Thrombocytopenia
- Hypersensitivity reactions
- Elevated blood pressure
- Hepatitis
Pregnancy & Lactation
- Inhibitory effect on prostaglandin synthesis
- Avoidance during late pregnancy
- Small amount passes into breast milk
- No evidence of adverse reactions in breast-fed infants
Precautions & Warnings
- Inhibition of renal prostaglandin synthesis
- Monitoring of cardiac and renal function
- Inhibition of platelet aggregation
- No significant influence on blood coagulation factors
- Monitoring of patients with coagulation disorders or drug therapy interfering with hemostasis
- Close monitoring if gastrointestinal disease or severe skin reactions occur
- Adverse eye findings reported
- Caution required with markedly reduced plasma albumin levels
- Masking of signs of infection
- Avoidance for patients who dislike or do not tolerate milk products
Use in Special Populations
- Not recommended for use in patients under 16 years of age
- Effects on ability to drive and use machines
Overdose Effects
- More pronounced signs and symptoms of undesirable effects
- Conventional measures to reduce absorption and speed up elimination
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Do not store above 30°C
- Protect from light & moisture
- Keep out of the reach of children