Xten 20 mg (Tablet)
Unit Price: ৳ 8.03 (3 x 10: ৳ 240.90)
Strip Price: ৳ 80.30
Medicine Details
| Category | Details |
|---|---|
| Generic | Tenoxicam |
| Company | Square pharmaceuticals plc |
Indications
- Rheumatoid arthritis
- Osteoarthritis
- Arthrosis
- Ankylosing spondylitis
- Tendinitis
- Bursitis
- Periarthritis of the shoulders
- Acute gout
- Strains
- Sprains
Pharmacology
- Non-steroidal anti-inflammatory drug (NSAID)
- Anti-inflammatory
- Analgesic
- Antipyretic
- Inhibits platelet aggregation
- Inhibits prostaglandin biosynthesis
- Inhibitor of human metalloproteinases
Dosage
- Standard dosage of 20 mg for most indications
- 40 mg for acute gout
- Therapeutic effect evident early in treatment
- Special dosage for elderly patients and patients with kidney or liver disease
Administration
- Tablets to be taken with a glass of water
- Preferable to take with a meal
Interaction
- Salicylate displacement
- Concurrent treatment with other NSAIDs
- Caution with methotrexate
- Effect on renal clearance of lithium
- Avoid concomitant administration with K-sparing diuretics
- Caution with antihypertensive drugs
- No interaction with antacids, cimetidine, warfarin, and phenprocoumon
Contraindications
- Hypersensitivity to the drug
- Induction of symptoms of asthma, rhinitis, or urticaria by salicylates or other NSAIDs
- Disease of the upper gastrointestinal tract
Side Effects
- Mild and transient undesirable effects reported
- Gastrointestinal discomfort, dyspepsia, and nausea
- Dizziness and headache
- Constipation, diarrhea, and vomiting
- Skin reactions including itching, rash, and urticaria
- Increase in BUN or creatinine
- Elevated liver enzyme activity
- Cardiovascular effects like palpitations
Pregnancy & Lactation
- Inhibitory effect on prostaglandin synthesis
- Avoid during late pregnancy
- Small amount traces into breast milk
- No evidence of adverse reactions in breast-fed infants
Precautions & Warnings
- Inhibition of renal prostaglandin synthesis
- Monitoring of renal function and salt-water balance
- Inhibition of platelet aggregation
- Close monitoring in case of gastrointestinal disease
- Immediate withdrawal in case of peptic ulceration or gastrointestinal bleeding
- Caution with severe skin reactions
- Ophthalmic evaluation for visual disturbances
- Caution with reduced plasma albumin levels
- Masking of signs of infection
- Avoidance in patients who dislike or do not tolerate milk products
Use in Special Populations
- Not recommended for use in patients under 16 years of age
- Effects on ability to drive and use machines
Overdose Effects
- Expectation of more pronounced undesirable effects
- Conventional measures to reduce absorption and speed up elimination
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Do not store above 30°C
- Protect from light & moisture
- Keep out of the reach of children