Oxiflam 20 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tenoxicam |
| Company | Ibn sina pharmaceuticals ltd |
Indications
- Rheumatoid arthritis
- Osteoarthritis
- Arthrosis
- Ankylosing spondylitis
- Tendinitis
- Bursitis
- Periarthritis of the shoulders
- Strains
- Sprains
- Acute gout
Pharmacology
- NSAID
- Anti-inflammatory
- Analgesic
- Antipyretic
- Platelet aggregation inhibitor
Dosage
- Standard dosage of 20 mg
- Acute gout: 40 mg for 2 days, then 20 mg for 5 days
- Therapeutic effect evident early in treatment
- Avoid daily doses higher than 20 mg for chronic disorders
- Reduction to a daily oral dose of 10 mg for maintenance
Administration
- Should be taken with a glass of water
- Preferable to take after a meal
Interaction
- Salicylate displaces the drug from protein-binding sites
- Concurrent treatment with salicylate or other NSAIDs should be avoided
- Caution with concurrent administration with methotrexate
- No significant interaction with gold, penicillamine, or probenecid
- May decrease renal clearance of lithium
- Avoid concurrent administration with K-sparing diuretics
- No clinically significant interaction noted with furosemide
- Attenuates the blood pressure-lowering effect of hydrochlorothiazide
- Might attenuate the antihypertensive effects of alpha-adrenergic blockers and ACE-inhibitors
- No interaction reported with centrally-acting alpha agonists or calcium channel blockers
- No significant interaction with atenolol, digitalis products, antacids, cimetidine, warfarin, phenprocoumon, low molecular weight heparin, or oral antidiabetic drugs
Contraindications
- Hypersensitivity to the drug
- Salicylates or other NSAIDs induce symptoms of asthma, rhinitis, or urticaria
- Upper gastrointestinal tract disease
Side Effects
- Gastrointestinal discomfort, dyspepsia, heartburn, nausea
- Dizziness, headache
- Constipation, diarrhea, stomatitis, gastritis, vomiting, ulcers, GI bleeding
- Fatigue, sleep disturbances, appetite loss, dry mouth, vertigo
- Itching, erythema, exanthema, rash, urticaria
- Increase in BUN or creatinine, edema
- Increased liver enzyme activity
- Palpitations
- Visual disturbances, anemia, agranulocytosis, leukopenia, thrombocytopenia
- Hypersensitivity reactions, elevated blood pressure, hepatitis
Pregnancy & Lactation
- Inhibitory effect on prostaglandin synthesis
- Avoid during late pregnancy
- Small amount passes into breast milk
- Infants should be weaned or the drug discontinued
Precautions & Warnings
- Inhibition of renal prostaglandin synthesis
- Monitoring of renal function and salt/water balance
- Inhibition of platelet aggregation and effects on hemostasis
- Careful observation in patients with coagulation disorders or receiving hemostasis-interfering drugs
- Closely monitor patients presenting with symptoms of gastrointestinal disease
- Discontinue treatment if severe skin reactions occur
- Ophthalmic evaluation recommended for patients with visual disturbances
- Caution required when plasma albumin levels are markedly reduced
- May mask signs of infection
- Not recommended for patients who dislike or do not tolerate milk products
Use in Special Populations
- Not recommended for use in patients under 16 years of age
- Effects on ability to drive and use machines
Overdose Effects
- Expectation of more pronounced undesirable effects
- Conventional measures to reduce absorption and speed up elimination
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- NSAIDs
Storage Conditions
- Do not store above 30°C
- Protect from light & moisture
- Keep out of the reach of children