Arthrofen 50 mg+200 mcg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Indications

  • Treatment of osteoarthritis
  • Treatment of rheumatoid arthritis
  • Prevention of NSAID-induced gastric ulcers
  • Prevention of duodenal ulcers

Pharmacology

  • Combination of Diclofenac Sodium and Misoprostol
  • NSAID with analgesic properties
  • GI mucosal protective prostaglandin E 1 analog
  • Mechanism related to prostaglandin synthetase inhibition

Dosage & Administration

  • Recommended dosage for osteoarthritis and rheumatoid arthritis
  • Different dosage options based on patient tolerance
  • Frequency of administration

Interaction

  • Interactions with aspirin, digoxin, antihypertensives, warfarin, oral hypoglycaemics, antacids, diuretics
  • Effects on plasma concentrations and bleeding risk

Contraindications

  • Hypersensitivity to Diclofenac or Misoprostol
  • Contraindicated in patients with asthma or urticaria after NSAID use

Side Effects

  • Common side effects like abdominal pain and diarrhea
  • Rare instances of severe dehydration
  • Self-limiting symptoms

Pregnancy & Lactation

  • Contraindicated in pregnant women
  • Presence in breast milk
  • Not recommended for nursing mothers

Precautions & Warnings

  • Monitor patients with underlying conditions
  • Dehydration risk

Use in Special Populations

  • Paediatric use not established
  • Safety and effectiveness in geriatric patients
  • Possible differences in sensitivity in elderly

Overdose Effects

  • Symptoms of Misoprostol overdose
  • Symptoms of Diclofenac overdose
  • Management of overdose

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Recommended storage temperature below 25°C
  • Protection from light

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