Miclofenac 50 mg+200 mcg (Tablet)

Unit Price: ৳ 10.07 (3 x 10: ৳ 302.16)

Strip Price: ৳ 100.72

Medicine Details

Category	Details
Generic	Diclofenac sodium misoprostol
Company	Square pharmaceuticals plc
Also available as	Miclofenac 75 mg tablet

Indications

Treatment of osteoarthritis
Treatment of rheumatoid arthritis
High risk of developing NSAID-induced gastric ulcers
High risk of developing NSAID-induced duodenal ulcers

Pharmacology

Contains Diclofenac Sodium
Contains Misoprostol
NSAID with analgesic properties
GI mucosal protective prostaglandin E1 analog
Mechanism of action related to prostaglandin synthetase inhibition

Dosage & Administration

Recommended dosage for osteoarthritis
Recommended dosage for rheumatoid arthritis
Dosage adjustment for patient intolerance

Interaction

Contraindicated with aspirin
Elevated digoxin levels
Inhibition of antihypertensives
Synergistic effects with warfarin
Effects on glucose metabolism
Interaction with antacids
Inhibition of diuretics activity

Contraindications

Hypersensitivity to Diclofenac
Hypersensitivity to Misoprostol
Contraindicated in asthma patients
Contraindicated in patients with urticaria
Contraindicated in patients with allergic-type reactions to aspirin or NSAIDs

Side Effects

Abdominal pain
Diarrhea
GI symptoms
Severe dehydration due to profound diarrhea

Pregnancy & Lactation

Contradicted in pregnant women
Presence in breast milk
Not recommended for nursing mothers

Precautions & Warnings

Monitoring in patients with inflammatory bowel disease
Careful monitoring for dehydration

Use in Special Populations

No established safety and effectiveness in pediatric patients
No overall differences in safety or effectiveness in geriatric patients
Likely greater sensitivity in some elderly patients

Overdose Effects

Misoprostol overdose effects
Diclofenac overdose effects

Therapeutic Class

Drugs for osteoarthritis
Drugs for rheumatoid arthritis
NSAIDs

Storage Conditions

Store below 25°C
Protect from light

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