Mifenac 50 mg+200 mcg (Tablet)

Unit Price: ৳ 8.00 (100's pack: ৳ 800.00)

Medicine Details

Category Details
Generic Diclofenac sodium misoprostol
Company Rephco pharmaceuticals ltd
Also available as
Mifenac 75 mg tablet

Indications

  • Treatment of osteoarthritis
  • Treatment of rheumatoid arthritis
  • High risk of developing NSAID-induced gastric and duodenal ulcers

Pharmacology

  • Combination product containing Diclofenac Sodium and Misoprostol
  • NSAID with analgesic properties
  • Gastrointestinal mucosal protective prostaglandin E 1 analog
  • Mechanism of action related to prostaglandin synthetase inhibition

Dosage & Administration

  • Recommended dosages for osteoarthritis and rheumatoid arthritis
  • Maximal GI mucosal protection
  • Different dosage options based on patient tolerance

Interaction

  • Interactions with aspirin, digoxin, antihypertensives, warfarin, oral hypoglycaemics, antacids, and diuretics

Contraindications

  • Contraindicated in hypersensitive patients
  • Contraindicated in patients who have experienced asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs

Side Effects

  • Common reported side effects including abdominal pain, diarrhea, and other GI symptoms
  • Rare instances of profound diarrhea leading to severe dehydration

Pregnancy & Lactation

  • Contraindicated in pregnant women due to the abortifacient property of Misoprostol
  • Not recommended for nursing mothers due to presence of Diclofenac Sodium in milk

Precautions & Warnings

  • Careful monitoring for patients with underlying conditions
  • Dehydration should be monitored carefully if prescribed

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients
  • No overall differences in safety or effectiveness observed in geriatric use

Overdose Effects

  • Misoprostol overdose effects and management
  • Diclofenac overdose effects

Therapeutic Class

  • Drugs for Osteoarthritis
  • Drugs used for Rheumatoid Arthritis
  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

Cool and dry storage below 25°C, protect from light

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