Avas 20 mg (Tablet)
Unit Price: ৳ 20.00 (1 x 14: ৳ 280.00)
Strip Price: ৳ 280.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Opsonin pharma ltd |
| Also available as |
Title and Category
- Avas 20 mg Tablet
- Cholesterol-lowering Medication
- Statins
- Anti-anginal & Anti-ischaemic drugs
Indications
- Reduction of total cholesterol
- Reduction of LDL cholesterol
- Reduction of apolipoprotein B levels
- Reduction of triglycerides levels
- Treatment of hypercholesterolemia
- Treatment of familial hypercholesterolaemia
- Treatment of mixed dyslipidemia
- Reduction of cardiac ischaemic events
- Reduction of cholesterol concentrations in diabetes mellitus patients
- Reduction of cholesterol concentrations in renal transplantation patients
Pharmacology
- Selective inhibitor of HMG-CoA reductase
- Lowers plasma cholesterol and lipoprotein levels
- Inhibits cholesterol synthesis in the liver
- Increases hepatic LDL receptors for enhanced uptake of LDL
- Rapidly absorbed after oral administration
- Maximum plasma concentrations occur within 1 to 2 hours
- Metabolized to ortho- and parahydroxylated derivatives
- Excreted primarily in bile
- Half-life of inhibitory activity for HMG-CoA reductase is 20 to 30 hours
Dosage & Administration
- Adults initial dose: 10 mg once daily
- Adults maximum dose: 80 mg once daily
- Children (10-18 years) initial dose: 10 mg once daily
- Children (10-18 years) maximum dose: 20 mg once daily
- Patient should be placed on a standard cholesterol-lowering diet before receiving Avas
Interactions
- Increased risk of myopathy with concurrent administration of certain drugs
- Plasma concentrations affected by coadministration with antacid, colestipol, digoxin, erythromycin, oral contraceptives, and warfarin
Contraindications
- Hypersensitivity to any component of Avas
- Active liver disease
- Unexplained persistent elevations of serum transaminases
- History of serious adverse reaction to prior HMG-CoA reductase inhibitors
Side Effects
- Constipation
- Flatulence
- Dyspepsia
- Abdominal pain
- Infection
- Headache
- Back pain
- Rash
- Asthenia
- Arthralgia
- Myalgia
Pregnancy & Lactation
- Contraindicated during pregnancy
- Safety not established in pregnant women
- No controlled clinical trials conducted in pregnant women
- Excretion in human milk unknown
- Potential for serious adverse reactions during breastfeeding
Precautions & Warnings
- Liver function tests should be performed before initiation of treatment and periodically thereafter
- Avas should be used with caution in patients who consume substantial quantities of alcohol or have a history of liver disease
- Avas therapy should be discontinued if markedly elevated CPK levels occur or myopathy is diagnosed or suspected
Use in Special Populations
- Plasma concentrations higher in healthy elderly subjects
- No clinically significant difference in LDL-C reduction between men and women
- Renal disease has no influence on plasma concentrations
- Hemodialysis not expected to significantly enhance clearance of Avas
- Plasma concentrations markedly increased in patients with chronic alcoholic liver disease
Overdose Effects
- Specific treatment not available for Avas overdose
- Symptomatic treatment and supportive measures instituted
- Liver function tests should be performed
- Serum CK levels should be monitored
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C33H35FN2O5
- Chemical Structure Image URL: [link to image here]
Commonly Asked Questions
- What is Avas 20 mg Tablet?
- How should I take Avas 20 mg Tablet?
- What are the uses of Avas 20 mg Tablet?
- What are the Side Effects of Avas 20 mg Tablet?
- What are the instructions for storage and disposal of Avas 20 mg Tablet?
- Is Avas 20 mg Tablet used for lowering cholesterol?
- Will taking Avas 20 mg Tablet increase my risk of diabetes?
- For how long do I need to take Avas 20 mg Tablet? Is it safe for long-term use?
- Does Avas 20 mg Tablet cause weight loss?
- Can I stop taking Avas 20 mg Tablet?
- Does Avas 20 mg Tablet cause memory loss?
- Does Avas 20 mg Tablet make you tired?
- Can Avas 20 mg Tablet be prescribed to children?
- Is Avas 20 mg Tablet a blood thinner?
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