Actemra 200 mg/10 ml (IV Infusion)
10 ml vial: ৳ 24,621.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tocilizumab |
| Company | Roche bangladesh ltd |
| Also available as |
Title
- Actemra (Tocilizumab)
Categories
- Medicine
- Rheumatoid Arthritis Treatment
- Pediatric Arthritis Treatment
- COVID-19 Treatment
Description
- Interleukin-6 (IL-6) Receptor Antagonist
- Recommended for Rheumatoid Arthritis, Juvenile Idiopathic Arthritis, COVID-19, Cytokine Release Syndrome, Giant Cell Arteritis, and Systemic Sclerosis-Associated Interstitial Lung Disease
Dimensions
- N/A
Color Options
- N/A
Functions
- Anti-inflammatory
- Immunosuppressive
- Cytokine Inhibitor
Materials
- Recombinant Humanized Anti-Human IL-6 Receptor Monoclonal Antibody
Technical Specifications
- Subcutaneous and Intravenous Dosage Forms
- Dosage Adjustment based on Patient's Body Weight
- Intravenous Infusion Period: 60 minutes
- Storage Temperature: 2°C to 8°C
Design Elements
- Monoclonal Antibody of Immunoglobulin IgG1K Subclass
Usability Features
- Treatment of Adults and Pediatric Patients (2 years of age and older)
- Can be used as Monotherapy or in Combination with Other Medications
Indications
- Rheumatoid Arthritis Treatment
- Polyarticular Juvenile Idiopathic Arthritis Treatment
- Systemic Juvenile Idiopathic Arthritis Treatment
- COVID-19 Treatment
- Cytokine Release Syndrome Treatment
- Giant Cell Arteritis Treatment
- Systemic Sclerosis-Associated Interstitial Lung Disease Treatment
Pharmacology
- Binds to Soluble and Membrane-Bound IL-6 Receptors
- Inhibits IL-6-Mediated Signaling
- Pleiotropic Pro-inflammatory Cytokine Inhibition
Dosage and Administration
- Dosage Adjustment based on Clinical Response
- Specific Dosage Recommendations for Different Conditions
Interaction
- Coadministration Caution with CYP3A4 Substrate Drugs
Contraindications
- Known Hypersensitivity to Tocilizumab
Side Effects
- Upper Respiratory Tract Infections
- Nasopharyngitis
- Headache
- Hypertension
- Increased ALT
- Injection Site Reactions
Pregnancy & Lactation
- May Cause Fetal Harm
- Consider Potential Benefit vs. Risk in Pregnancy
- Consider Importance of Drug to Mother in Nursing
Precautions & Warnings
- Serious Infections Precaution
- Tuberculosis Evaluation
- Gastrointestinal Perforation Caution
- Hepatotoxicity Monitoring
- Hypersensitivity Reactions Awareness
- Live Vaccines Avoidance
- Biological DMARDs Avoidance
Use in Special Populations
- Pediatric Use Specifics
- Geriatric Use Caution
- Hepatic Impairment Unstudied
- Renal Impairment Considerations
Overdose Effects
- Monitor for Adverse Reactions
- Provide Symptomatic Treatment for Adverse Reactions
Therapeutic Class
- Drugs used for Rheumatoid Arthritis
Storage Conditions
- Temperature Range: 2°C to 8°C, Do Not Freeze