Uristat 40 mg (Tablet)
Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Febuxostat |
| Company | Ibn sina pharmaceuticals ltd |
| Also available as |
Indications
- Chronic management of hyperuricemia in patients with gout
Pharmacology
- Non-purine, selective xanthine oxidase (XO) inhibitor
- Decreases serum uric acid level
- Inhibits xanthine oxidase
Dosage & Administration
- Recommended starting dose of Febuxostat 40 mg tablet once daily
- Dose adjustment for Tumor Lysis Syndrome
- Gout flare management
- Renal and hepatic impairment dosage
- Pediatric use safety information
Interaction
- Inhibition of XO by Uristat and its impact on other drugs
- Co-administration with rosiglitazone or other CYP2C8 substrates
- Impact of medicinal products that inhibit glucuronidation
- Effect of potent inducers of UGT enzymes
- Co-administration with colchicine, indomethacin, hydrochlorothiazide, warfarin, and antacids
Contraindications
- Contraindicated in patients being treated with azathioprine, mercaptopurine, or theophylline
Side Effects
- Commonly reported adverse reactions including gout flares, liver function abnormalities, diarrhea, nausea, headache, rash, and edema
- Rare serious hypersensitivity reactions
Pregnancy & Lactation
- Pregnancy Category C
- Usage during pregnancy and caution during breastfeeding
Precautions & Warnings
- Increased gout flare observations during treatment initiation
- Monitoring for signs and symptoms of cardiovascular events
- Monitoring liver function tests periodically
Overdose Effects
- Febustat studied in healthy subjects in doses up to 300 mg daily for seven days without evidence of dose-limiting toxicities
Therapeutic Class
- Drugs used in Gout
Storage Conditions
- Keep below 30°C temperature
- Away from light & moisture
- Keep out of the reach of children