Baclomark 10 mg (Tablet)
Unit Price: ৳ 6.02 (30's pack: ৳ 180.60)
Medicine Details
Category | Details |
---|---|
Generic | Baclofen |
Company | Hallmark pharmaceuticals ltd |
Indications
- Spasticity resulting from multiple sclerosis
- Flexor spasms and concomitant pain
- Rheumatic disorders
- Spinal cord injuries
- Cerebrovascular accidents
Pharmacology
- Inhibition of monosynaptic and polysynaptic reflexes
- Stimulation of GABA receptors
- Antinociceptive effect
Dosage & Administration
- 5 mg 3 times daily for adults & children over 10 years
- Gradually increased dosage
- Maximum daily dosage of 100 mg
- Different dosage for children under 10 years
Interaction
- Increased sedation with CNS acting agents, alcohol or synthetic opiates
- Potential fall in blood pressure with antihypertensives
- Potentiation with tricyclic antidepressants
- Possible adverse effects with levodopa and carbidopa
- Interaction with MAO inhibitors
- Caution with magnesium sulphate or other neuromuscular blocking agents
Contraindications
- Hypersensitivity to any component of the product
Side Effects
- Transient drowsiness
- Daytime sedation
- Dizziness
- Weakness
- Fatigue
- Potential CNS effects
- Cardiovascular effects
- Gastrointestinal effects
- Genitourinary effects
- Other rare side effects
Pregnancy & Lactation
- Pregnancy category B3
- Crossing the placental barrier
- Use only if benefits outweigh hazards
- Excretion in breast milk
Precautions & Warnings
- Lower doses for impaired renal function
- Close monitoring for psychotic disorders
- Seizure risk for epilepsy patients
- Caution in patients with peptic ulcers, cerebrovascular diseases, or hepatic, renal or respiratory failure
- Respiratory and cardiovascular function monitoring
- Bladder emptying improvements
- Poor tolerance in stroke patients
- Periodic laboratory tests for hepatic diseases or diabetes mellitus
Overdose Effects
- Importance of gastric lavage in severe overdose
Therapeutic Class
- Centrally acting Skeletal Muscle Relaxants
Storage Conditions
- Keep below 30°C
- Away from light & moisture
- Keep out of the reach of children