Avocard 20 mg (Tablet)

Unit Price: ৳ 18.00 (30's pack: ৳ 540.00)

Medicine Details

Category Details
Generic Atorvastatin calcium
Company The white horse pharmaceuticals ltd
Also available as
Avocard 10 mg tablet

Title

  • Avocard 20 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Description

  • Avocard is indicated as an adjunct to diet to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels in several diseases.

Indications

  • Reduce total cholesterol and LDL cholesterol in patients with heterozygous and homozygous familial hypercholesterolaemia
  • Reduce elevated cholesterol and triglycerides in patient with mixed dyslipidemia (Fredrickson Type Ia and Ib)
  • Treat patients with elevated serum triglyceride levels in hypertriglyceridemia (Fredrickson Type IV)
  • Treat patients with dysbetalipoproteinaemia (Fredrickson Type III)
  • Reduce cardiac ischaemic events in patients with coronary artery disease with elevated LDL-cholesterol level
  • Reduce total and LDL-cholesterol concentrations in patients with hypercholesterolemia associated with diabetes mellitus or renal transplantation

Mode of Action

  • Selective inhibitor of HMG-CoA reductase
  • Lowers plasma cholesterol and lipoprotein levels by inhibiting HMG-CoA reductase
  • Increases the number of hepatic LDL receptors for enhanced uptake and catabolism of LDL
  • Rapidly absorbed after oral administration with maximum plasma concentrations occurring within 1 to 2 hours

Dosage & Administration

  • Adults: Usually 10 mg once daily; may be increased at intervals of at least 4 weeks to max. 80 mg once daily
  • Child (10-18 years): Initially 10 mg once daily, increased if necessary at intervals of at least 4 weeks to usual max. 20 mg once daily

Interaction

  • Increased risk of myopathy with concurrent administration of cyclosporine, fibric acid derivatives, niacin, erythromycin, azole antifungals
  • Plasma concentrations of atorvastatin decreased when coadministered with antacid, and increased with erythromycin
  • Increased AUC values for norethindrone and ethinyl estradiol when coadministered with an oral contraceptive

Contraindications

  • Hypersensitivity to any component of the medication
  • Active liver disease or unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infections
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Not known whether atorvastatin or its metabolites are excreted in human milk

Precautions & Warnings

  • Liver function tests should be performed before the initiation of treatment and periodically thereafter
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected
  • Use with caution in patients who consume substantial quantities of alcohol or have a history of liver disease

Use in Special Populations

  • Plasma concentrations are higher in healthy elderly subjects than in young adults
  • No clinically significant difference in LDL-C reduction between men and women
  • No dose adjustment necessary in patients with renal dysfunction

Overdose Effects

  • Specific treatment is not available for atorvastatin overdose
  • Liver function tests should be performed and serum CK levels should be monitored

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C33H35FN2O5
  • Chemical Structure available

Commonly Asked Questions

  • What is Avocard 20 mg Tablet?
  • How should I take Avocard 20 mg Tablet?
  • What are the uses of Avocard 20 mg Tablet?
  • What are the Side Effects of Avocard 20 mg Tablet?
  • What are the instructions for storage and disposal Avocard 20 mg Tablet?
  • Is Avocard 20 mg Tablet used for lowering cholesterol?
  • Will taking Avocard 20 mg Tablet increase my risk of diabetes?
  • For how long do I need to take Avocard 20 mg Tablet? Is it safe for long-term use?
  • Does Avocard 20 mg Tablet cause weight loss?
  • Can I stop taking Avocard 20 mg Tablet?
  • Does Avocard 20 mg Tablet cause memory loss?
  • Does Avocard 20 mg Tablet make you tired?
  • Can Avocard 20 mg Tablet be prescribed to children?
  • Is Avocard 20 mg Tablet a blood thinner?
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