Flexibac 25 mg (Tablet)
Unit Price: ৳ 20.06 (2 x 10: ৳ 401.20)
Strip Price: ৳ 200.60
Medicine Details
| Category | Details |
|---|---|
| Generic | Baclofen |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Spasticity resulting from multiple sclerosis
- Flexor spasms and concomitant pain, clonus and muscular rigidity
- Skeletal muscle spasm resulting from rheumatic disorders
- Spinal cord injuries and other spinal cord diseases
- Cerebrovascular accidents or neoplastic or degenerative brain disease
Pharmacology
- Baclofen inhibits both monosynaptic and polysynaptic reflexes at the spinal level
- Stimulates the GABA receptors
- Inhibits the release of glutamate and aspartate
- Exerts an antinociceptive effect
Dosage & Administration
- Adult & children over 10 years: 5 mg 3 times daily, preferably with or after food, gradually increased; max. 100 mg daily
- Children <10 years: Treatment is usually started with 2.5 mg (2.5 ml) given 4 times daily then raised according to requirement
Interaction
- Increased sedation may occur if Flexibac is taken with agents acting on the central nervous system, alcohol or synthetic opiates
- Combined treatment with Flexibac and antihypertensives is likely to increase the fall in blood pressure
- The concomitant administration of Flexibac and tricyclic antidepressants may potentiate the pharmacological effects of Flexibac
Contraindications
- Baclofen is contraindicated in patients with hypersensitivity to any component of this product
Side Effects
- Transient drowsiness
- Daytime sedation
- Dizziness
- Weakness
- Fatigue
- Headache
- Insomnia
- Euphoria
- Depression
- Nausea
- Constipation
Pregnancy & Lactation
- Safe use of Baclofen during pregnancy has not been established
- Baclofen crosses the placental barrier
Precautions & Warnings
- Lower doses should be used for patients with impaired renal function or those undergoing chronic haemodialysis
- Patients with psychotic disorders, schizophrenia, depressive or manic disorders should be treated cautiously and closely monitored
Overdose Effects
- Gastric lavage is important in case of severe overdose
Therapeutic Class
- Centrally acting Skeletal Muscle Relaxants
Storage Conditions
- Keep below 30°C temperature, away from light & moisture