Myorel 5 mg (Tablet)

Unit Price: ৳ 5.00 (3 x 10: ৳ 150.00)
Strip Price: ৳ 50.00

Medicine Details

Title and Category

  • Myorel - Baclofen Tablet
  • Centrally acting Skeletal Muscle Relaxants

Indications

  • Spasticity resulting from multiple sclerosis
  • Flexor spasms and concomitant pain, clonus and muscular rigidity
  • Skeletal muscle spasm resulting from rheumatic disorders
  • Spinal cord injuries and other spinal cord diseases
  • Cerebrovascular accidents or neoplastic or degenerative brain disease

Pharmacology

  • Inhibits both monosynaptic and polysynaptic reflexes at the spinal level
  • Stimulates the GABAB receptors
  • Inhibits the release of glutamate and aspartate
  • Produces CNS depression
  • Exerts antinociceptive effect

Dosage & Administration

  • Recommended dosage for adults and children over 10 years
  • Initial dose of 5 mg 3 times daily, gradually increased
  • Maximum daily dosage of 100 mg
  • Specific dosage recommendations for children under 10 years

Interactions

  • Increased sedation when taken with CNS acting agents, alcohol, or synthetic opiates
  • Likely increase in blood pressure when combined with antihypertensives
  • Potentiation of effects when combined with tricyclic antidepressants
  • Reports of mental confusion and other effects when taken with levodopa, carbidopa, or MAO inhibitors

Contraindications

  • Hypersensitivity to any component of the product

Side Effects

  • Transient drowsiness
  • Daytime sedation
  • Dizziness
  • Weakness
  • Fatigue
  • Various CNS related side effects
  • Hypotension
  • Gastrointestinal effects
  • Genitourinary effects
  • Other effects such as rash, pruritus, ankle edema, weight gain
  • Muscular hypotonia

Pregnancy & Lactation

  • Pregnancy category B3
  • Excretion in breast milk

Precautions & Warnings

  • Lower doses for patients with impaired renal function or undergoing haemodialysis
  • Cautious use for patients with psychotic disorders, epilepsy, peptic ulcers, and more
  • Monitoring of respiratory and cardiovascular function

Overdose Effects

  • Importance of gastric lavage in case of severe overdose

Storage Conditions

  • Keep below 30°C temperature
  • Away from light & moisture
  • Keep out of the reach of children

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