Skelofen 10 mg (Tablet)

Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)

Strip Price: ৳ 90.00

Medicine Details

Adult & children over 10 years: 5 mg 3 times daily
preferably with or after food
gradually increased; max. 100 mg daily
Children <10 years: Treatment is usually started with 2.5 mg given 4 times daily then raised according to requirement
Daily maintenance dose—12 month-2 years: 10-20 mg
2 years-6 years: 20-30 mg
6 years-10 years: 30-60 mg

Increased sedation may occur if taken with agents acting on the central nervous system
Combined treatment with antihypertensives is likely to increase the fall in blood pressure
The concomitant administration of and tricyclic antidepressants may potentiate the pharmacological effects
In patients with Parkinsons disease receiving treatment with and levodopa and carbidopa, there have been several reports of mental confusion, hallucinations, headaches, nausea and agitation
The concurrent use of MAO inhibitors and may result in increased CNS depressant effects
Caution should be exercised when administering and magnesium sulphate or other neuromuscular blocking agents since a synergistic effect may theoretically occur

contraindicated in patients with hypersensitivity to any component of this product

transient drowsiness
daytime sedation
dizziness
weakness
fatigue
Central Nervous System: Headache, insomnia, euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, co-ordination disorder, tremor, rigidity, dystonia, ataxia, blurred vision, nystagmus, strabismus, miosis, mydriasis, diplopia, dysarthria, epileptic seizures, respiratory depression
Cardiovascular: Hypotension, dyspnoea, palpitation, chest pain, syncope
Gastrointestinal: Nausea, constipation, dry mouth, anorexia, taste disorder, abdominal pain, vomiting, diarrhoea, positive test for occult blood in stool
Genitourinary: Urinary frequency, enuresis, urinary retention, dysuria, impotence, inability to ejaculate, nocturia, haematuria
Other: Rash, pruritus, ankle oedema, excessive perspiration, weight gain, nasal congestion, visual disturbances, hepatic function disorders, paradoxical increase in spasticity

Pregnancy category B3
Safe use during pregnancy has not been established
Baclofen crosses the placental barrier
Baclofen is excreted in breast milk however evidence to date suggests that the quantities are so small that no undesirable effects on the infant would be expected

Lower doses should be used for patients with impaired renal function or those undergoing chronic haemodialysis
Patients with psychotic disorders, schizophrenia, depressive or manic disorders or confusional states should be treated cautiously and closely monitored
In patients with epilepsy and muscle spasticity, may be used under appropriate supervision and provided that adequate anticonvulsive therapy is continued
Skelofen should be used with caution in patients with or with a history of peptic ulcers, cerebrovascular diseases, or hepatic, renal or respiratory failure
Careful monitoring of respiratory and cardiovascular function is essential especially in patients with cardiopulmonary disease and respiratory muscle weakness
During treatment with Skelofen, neurogenic disturbances affecting emptying of the bladder may improve
Skelofen has not significantly benefited patients with stroke
Appropriate laboratory tests should be performed periodically in patients with hepatic diseases or diabetes mellitus