Fenobac 5 mg/5 ml (Oral Solution)
100 ml bottle: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Baclofen |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Indications
- spasticity resulting from multiple sclerosis
- flexor spasms and concomitant pain
- clonus and muscular rigidity
- skeletal muscle spasm resulting from rheumatic disorders
- spinal cord injuries and other spinal cord diseases
- cerebrovascular accidents or neoplastic or degenerative brain disease
Pharmacology
- inhibits monosynaptic and polysynaptic reflexes
- stimulates GABA B receptors
- inhibits release of glutamate and aspartate
- produces CNS depression
- exerts antinociceptive effect
Dosage & Administration
- 5 mg 3 times daily for adults & children over 10 years
- gradually increase dosage
- max. 100 mg daily
- gradual increase of dosage for children under 10 years based on requirement
Interaction
- increased sedation with CNS agents, alcohol, and synthetic opiates
- potentiates pharmacological effects with tricyclic antidepressants
- mental confusion in Parkinson's patients with levodopa and carbidopa
- increased CNS depressant effects with MAO inhibitors
- caution with magnesium sulphate and neuromuscular blocking agents
Contraindications
- hypersensitivity to any component of the product
Side Effects
- transient drowsiness
- daytime sedation
- dizziness
- weakness
- fatigue
- headache
- insomnia
- euphoria
- excitement
- depression
- confusion
- hallucinations
- paraesthesia
- nightmares
- muscle pain
- tremor
- hypotension
- dyspnoea
- nausea
- constipation
- dry mouth
- urinary frequency
- enuresis
- rash
- pruritus
- ankle oedema
- excessive perspiration
- weight gain
- hepatic function disorders
- increase in spasticity
Pregnancy & Lactation
- Pregnancy category B3
- safe use not established
- crosses placental barrier
- administer only if benefits outweigh hazards
- excreted in breast milk with minimal expected effects on infant
Precautions & Warnings
- lower doses for impaired renal function or chronic haemodialysis
- caution with psychotic disorders, schizophrenia, depressive or manic disorders
- appropriate supervision for epilepsy patients
- caution with peptic ulcers, cerebrovascular diseases, hepatic, renal or respiratory failure
- monitor respiratory and cardiovascular function
- caution with bladder emptying and sphincter hypertonia
- poor tolerance in stroke patients
- appropriate lab tests for hepatic diseases or diabetes mellitus
Overdose Effects
- gastric lavage in case of severe overdose
Therapeutic Class
- Centrally acting Skeletal Muscle Relaxants
Storage Conditions
- Keep below 30°C temperature
- away from light & moisture
- keep out of the reach of children