Starbac 10 mg (Tablet)
Unit Price: ৳ 8.00 (30's pack: ৳ 240.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Baclofen |
| Company | Leon pharmaceuticals ltd |
| Also available as |
Indications
- spasticity resulting from multiple sclerosis
- flexor spasms and concomitant pain
- clonus and muscular rigidity
- skeletal muscle spasm resulting from rheumatic disorders
- spinal cord injuries and other spinal cord diseases
- cerebrovascular accidents or neoplastic or degenerative brain disease
Pharmacology
Baclofen inhibits both monosynaptic and polysynaptic reflexes at the spinal level by stimulating the GABAB receptors
Dosage & Administration
- Adult & children over 10 years: 5 mg 3 times daily, preferably with or after food, gradually increased; max. 100 mg daily
- Children <10 years: Treatment is usually started with 2.5 mg (2.5 ml) given 4 times daily then raised according to requirement
Interaction
- Increased sedation with CNS agents
- Increased fall in blood pressure with antihypertensives
- Potentiation with tricyclic antidepressants
- Mental confusion and other effects with parkinson's medications
- CNS depressant effects with MAO inhibitors
- Synergistic effect with neuromuscular blocking agents
Contraindications
Hypersensitivity to any component of this product
Side Effects
- Central Nervous System:
- Headache
- insomnia
- euphoria
- excitement
- depression
- confusion
- hallucinations
- tremor
- rigidity
- dystonia
- ataxia
- blurred vision
- seizures
- respiratory depression
- Cardiovascular:
- Hypotension
- dyspnoea
- palpitation
- Gastrointestinal:
- Nausea
- constipation
- dry mouth
- abdominal pain
- vomiting
- diarrhoea
- Genitourinary:
- Urinary frequency
- enuresis
- urinary retention
- Other:
- Rash
- pruritus
- ankle oedema
- excessive perspiration
- weight gain
- visual disturbances
- hepatic function disorders
Pregnancy & Lactation
- Category: B3
- Use during pregnancy: Only if benefits outweigh possible hazards
- Excretion in breast milk: Quantities are so small that no undesirable effects on the infant would be expected
Precautions & Warnings
- Lower doses for impaired renal function
- Cautious treatment for patients with psychotic disorders or epilepsy
- Caution for patients with peptic ulcers, cerebrovascular diseases, or hepatic, renal or respiratory failure
Overdose Effects
Gastric lavage is important in case of severe overdose
Therapeutic Class
Centrally acting Skeletal Muscle Relaxants
Storage Conditions
Keep below 30°C temperature, away from light & moisture