Divastin 20 mg (Tablet)
Unit Price: ৳ 20.00 (2 x 14: ৳ 560.00)
Strip Price: ৳ 280.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Drug international ltd |
| Also available as |
Title and Category
- Divastin 20 mg Tablet
- Medicine
- Pharmaceutical
Dosage Form
- Tablet
Dosage Strength
- 20 mg
Effective Ingredient
- Atorvastatin
Indications
- Reduction of elevated total cholesterol
- Lowering of LDL cholesterol
- Reducing apolipoprotein B levels
- Management of triglycerides
Diseases Indicated
- Familial hypercholesterolaemia
- Mixed dyslipidemia
- Hypertriglyceridemia
- Dysbetalipoproteinaemia
- Coronary artery disease
- Hypercholesterolemia exacerbated by diabetes mellitus or renal transplantation
Pharmacological Action
- Selective inhibitor of HMG-CoA reductase
- Lowers plasma cholesterol and lipoprotein levels
- Increases hepatic LDL receptors
Absorption
- Rapidly absorbed after oral administration
- Maximum plasma concentrations within 1 to 2 hours
Metabolism
- Extensively metabolized to ortho- and parahydroxylated derivatives
- Metabolized by cytochrome P450 3A4
Distribution
- Approximately 98% bound to plasma proteins
Excretion
- Eliminated primarily in bile
Dosage and Administration
- Adults: Usually 10 mg once daily; may be increased to max 80 mg once daily
- Child (10-18 years): Initially 10 mg once daily, increased if necessary to max 20 mg once daily
Interaction with Other Drugs
- Concurrent administration with certain drugs increases risk of myopathy
- Plasma concentrations altered when coadministered with antacid, colestipol, digoxin, erythromycin, oral contraceptives, or warfarin
Contraindications
- Hypersensitivity to any component
- Active liver disease or unexplained persistent elevations of serum transaminases
- History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors
Side Effects
- Constipation
- Flatulence
- Dyspepsia
- Abdominal pain
- Infection
- Headache
- Back pain
- Rash
- Asthenia
- Arthralgia
- Myalgia
Pregnancy & Lactation
- Contraindicated during pregnancy
- Not known if excreted in human milk
- Treatment should be suspended during pregnancy or breastfeeding
Precautions & Warnings
- Liver function tests should be performed before initiation of treatment
- Use with caution in patients who consume substantial quantities of alcohol or have a history of liver disease
Use in Special Populations
- Plasma concentrations are higher in healthy elderly subjects
- Pharmacokinetic data in the pediatric population not available
- No clinically significant difference in LDL-C reduction between men and women
Overdose Effects
- Specific treatment not available
- Symptomatic treatment and supportive measures should be instituted
Therapeutic Class
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C33H35FN2O5
Commonly Asked Questions
- What is Divastin 20 mg Tablet?
- How should I take Divastin 20 mg Tablet?
- What are the uses of Divastin 20 mg Tablet?
- What are the Side Effects of Divastin 20 mg Tablet?
- What are the instructions for storage and disposal of Divastin 20 mg Tablet?
- Is Divastin 20 mg Tablet used for lowering cholesterol?
- Will taking Divastin 20 mg Tablet increase my risk of diabetes?
- For how long do I need to take Divastin 20 mg Tablet? Is it safe for long-term use?
- Does Divastin 20 mg Tablet cause weight loss?
- Can I stop taking Divastin 20 mg Tablet?
- Does Divastin 20 mg Tablet cause memory loss?
- Does Divastin 20 mg Tablet make you tired?
- Can Divastin 20 mg Tablet be prescribed to children?
- Is Divastin 20 mg Tablet a blood thinner?
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