Histacin 2 mg/5 ml (Syrup)
Medicine Details
| Category | Details |
|---|---|
| Generic | Chlorpheniramine maleate |
| Company | Jayson pharmaceuticals ltd |
| Also available as |
Indications
- Urticaria
- Sensitivity reactions
- Angioneurotic edema
- Vasomotor rhinitis
- Cough
- Common cold
- Motion sickness
- Other allergic conditions
Pharmacology
Chlorpheniramine Maleate is an alkylamine antihistamine and one of the most potent histamine H1-receptor blocking agents, causing less sedation than promethazine. It exerts its effects by competitively blocking H1-receptor.
Dosage & Administration
- Adult: Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily.
- Child:
- 6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily.
- 2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily.
- 1-2 years: 1 mg twice daily.
- Below 1 year: not recommended
Interaction
Reported to be incompatible with calcium chloride, kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium, and meglumine adipiodone
Contraindications
Contraindicated in patients hypersensitive to this agent, in newborn or premature infants
Side Effects
Well-tolerated, but may cause drowsiness, dizziness, muscular weakness, and gastrointestinal upset
Pregnancy & Lactation
Not recommended for use in lactating mothers and during the first trimester of pregnancy
Precautions & Warnings
Use with caution in patients with glaucoma and prostatic hypertrophy. Caution should be taken in driving vehicles and operating machinery during therapy
Overdose Effects
CNS depression, CNS stimulation, tinnitus, blurred vision, dizziness, hypotension. Atropine-like signs and symptoms are more likely in children.
Therapeutic Class
Sedating Anti-histamine
Storage Conditions
Store in a cool (Below 25°C temperature) and dry place protected from light. Keep out of the reach of children