Histaco 2 mg/5 ml (Syrup)

60 ml bottle: ৳ 11.70

Medicine Details

Indications

  • Urticaria
  • Sensitivity reactions
  • Angioneurotic edema
  • Vasomotor rhinitis
  • Cough
  • Common cold
  • Motion sickness
  • Other allergic conditions

Pharmacology

  • Chlorpheniramine Maleate is an alkylamine antihistamine
  • Potent histamine H1-receptor blocking agent
  • Causes less sedation than promethazine
  • Exerts effects by competitively blocking H1-receptor

Dosage & Administration

  • Usual adult dose: 4 mg every 4-6 hours, maximum 24 mg daily
  • Child dose: 2 mg every 4-6 hours for 6-12 years, maximum 12 mg daily
  • Child dose: 1 mg every 4-6 hours for 2-5 years, maximum 6 mg daily
  • Child dose: 1 mg twice daily for 1-2 years
  • Not recommended for use in children below 1 year old

Interaction

  • Incompatible with calcium chloride
  • Incompatible with kanamycin sulfate
  • Incompatible with noradrenaline acid tartrate
  • Incompatible with pentobarbital sodium
  • Incompatible with meglumine adipiodone

Contraindications

  • Contraindicated in patients hypersensitive to this agent
  • Contraindicated in newborn or premature infants

Side Effects

  • Well-tolerated in general
  • Potential side effects: drowsiness, dizziness, muscular weakness, gastrointestinal upset

Pregnancy & Lactation

  • Not recommended for use in lactating mothers
  • Not recommended for use in pregnancy, especially during the first trimester

Precautions & Warnings

  • Use with caution in patients with glaucoma
  • Use with caution in patients with prostatic hypertrophy
  • Caution required in driving vehicles and operating machinery during therapy

Overdose Effects

  • Central Nervous System (CNS) depression including sedation, apnea, CV collapse
  • CNS stimulation including insomnia, hallucinations, tremors, convulsions
  • Other potential effects: tinnitus, blurred vision, dizziness, ataxia, hypotension
  • Stimulation and atropine-like signs and symptoms more likely in children

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Store in a cool place below 25°C temperature
  • Store in a dry place protected from light
  • Keep out of the reach of children

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