Histal 2 mg/5 ml (Syrup)

60 ml bottle: ৳ 20.00

Medicine Details

Category Details
Generic Chlorpheniramine maleate
Company Opsonin pharma ltd
Also available as
Histal 4 mg tablet

Indications

  • Urticaria
  • Sensitivity reactions
  • Angioneurotic edema
  • Vasomotor rhinitis
  • Cough
  • Common cold
  • Motion sickness
  • Other allergic conditions

Pharmacology

Chlorpheniramine Maleate is an alkylamine antihistamine with potent histamine H1-receptor blocking effects. It causes less sedation than promethazine and exerts its effects by competitively blocking H1-receptors.

Dosage & Administration

  • Adult: Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily
  • Child:
    • 6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily
    • 2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily
    • 1-2 years: 1 mg twice daily
    • Below 1 year: Chlorpheniramine Maleate is not recommended

Interaction

Chlorphenamine maleate has been reported to be incompatible with calcium chloride, kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium, and meglumine adipiodone

Contraindications

Chlorpheniramine is contraindicated in patients hypersensitive to this agent, in newborn or premature infants

Side Effects

  • Drowsiness
  • Dizziness
  • Muscular weakness
  • Gastrointestinal upset

Pregnancy & Lactation

This drug should not be used in lactating mothers and in pregnancy, especially during the first trimester

Precautions & Warnings

Histal should be used with caution in patients with glaucoma and prostatic hypertrophy. Caution should be taken in driving vehicles and operating machinery during therapy with chlorpheniramine

Overdose Effects

  • CNS depression (including sedation, apnea, CV collapse)
  • CNS stimulation (including insomnia, hallucination, tremors, convulsions)
  • Tinnitus
  • Blurred vision
  • Dizziness
  • Ataxia
  • Hypotension
  • Stimulation and atropine-like signs and symptoms (including dry mouth, fixed dilated pupils, flushing, hyperthermia, Gl symptoms) more likely in children

Therapeutic Class

Sedating Antihistamine

Storage Conditions

Store in a cool, dry place below 25°C and protected from light. Keep out of the reach of children

Related Brands