Sedilux-M 2 mg/5 ml (Syrup)

100 ml bottle: ৳ 21.70

Medicine Details

Indications

  • Urticaria
  • Sensitivity reactions
  • Angioneurotic edema
  • Vasomotor rhinitis
  • Cough
  • Common cold
  • Motion sickness
  • Allergic conditions

Pharmacology

Chlorpheniramine Maleate is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine. Chlorpheniramine Maleate exerts its effects by competitively blocking H1-receptor.

Dosage & Administration

  • Adult: Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily.
  • Child:
    • 6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily
    • 2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily
    • 1-2 years: 1 mg twice daily
  • Below 1 year: Use not recommended

Interaction

Chlorphenamine maleate has been reported to be incompatible with calcium chloride, kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium, and meglumine adipiodone

Contraindications

Contraindicated in patients hypersensitive to this agent, in newborn or premature infants

Side Effects

Well-tolerated, but sometimes may cause drowsiness, dizziness, muscular weakness, and gastrointestinal upset

Pregnancy & Lactation

Not recommended for use in lactating mothers and during the first trimester of pregnancy

Precautions & Warnings

Should be used with caution in patients with glaucoma and prostatic hypertrophy. Caution should be taken when driving vehicles and operating machinery during therapy with chlorpheniramine

Overdose Effects

CNS depression, CNS stimulation, tinnitus, blurred vision, dizziness, hypotension, atropine-like signs and symptoms are more likely in children

Therapeutic Class

Sedating Anti-histamine

Storage Conditions

Store in a cool and dry place protected from light at a temperature below 25°C. Keep out of the reach of children

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