G-Atorvast 10 mg (Tablet)

Unit Price: ৳ 8.05 (3 x 10: ৳ 241.50)
Strip Price: ৳ 80.50

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Gonoshasthaya pharma ltd
Also available as
G atorvast 20 mg tablet

Indications

  • Adjunct to diet to reduce elevated total cholesterol levels
  • Adjunct to diet to reduce elevated LDL cholesterol levels
  • Adjunct to diet to reduce elevated apolipoprotein B levels
  • Adjunct to diet to reduce elevated triglyceride levels
  • Treatment for heterozygous familial hypercholesterolaemia
  • Treatment for homozygous familial hypercholesterolaemia
  • Treatment for mixed dyslipidemia (Fredrickson Type Ia and Ib)
  • Treatment for hypertriglyceridaemia (Fredrickson Type IV)
  • Treatment for dysbetalipoproteinaemia (Fredrickson Type III)
  • Reduce cardiac ischaemic events in patients with coronary artery disease
  • Reduction of total and LDL-cholesterol concentrations in patients with diabetes mellitus or renal transplantation

Pharmacology

  • Selective inhibitor of HMG-CoA reductase
  • Lowers plasma cholesterol and lipoprotein levels
  • Increases hepatic LDL receptors for enhanced uptake of LDL
  • Rapidly absorbed after oral administration
  • Maximum plasma concentrations occur within 1 to 2 hours

Dosage & Administration

  • Recommended starting dose of 10 or 20 mg once daily
  • Maximum dose of 80 mg once daily
  • Can be administered as a single dose at any time of the day
  • Dose adjustment based on lipid levels analysis

Interaction

  • Increased risk of myopathy with concurrent administration of certain drugs
  • Plasma concentrations affected by coadministration with antacid and colestipol
  • Altered levels of digoxin and oral contraceptives when coadministered
  • No clinically significant effect on prothrombin time when administered with warfarin

Contraindications

  • Hypersensitivity to any component of the medication
  • Active liver disease or unexplained persistent elevations of serum transaminases
  • History of serious adverse reaction to HMG-CoA reductase inhibitors

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Potential toxicity to reproduction based on animal studies

Precautions & Warnings

  • Liver function tests should be performed before initiation of treatment
  • Discontinue therapy if markedly elevated CPK levels occur
  • Caution in patients with substantial alcohol consumption or liver disease

Use in Special Populations

  • Higher plasma concentrations in healthy elderly subjects
  • Greater degree of LDL-lowering in elderly patients
  • Pharmacokinetic data not available in pediatric population
  • No clinically significant difference in LDL-C reduction between men and women

Overdose Effects

  • Specific treatment not available for atorvastatin overdose
  • Liver function tests should be performed
  • Serum CK levels should be monitored

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Keep in dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula: C33H35FN2O5

Common Questions about G-Atorvast 10 mg Tablet

  • Selective inhibitor of HMG-CoA reductase
  • Used to avoid heart attacks and treat hypercholesterolemia
  • Instructions for administration, storage, and disposal
  • Possible side effects and their management
  • Long-term use and safety considerations

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