Lipex 20 mg (Tablet)

Unit Price: ৳ 18.00 (2 x 10: ৳ 360.00)
Strip Price: ৳ 180.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Orion pharma ltd
Also available as
Lipex 10 mg tablet

Title

  • Lipex 20 mg Tablet

Categories

  • Cholesterol-lowering Medication
  • Cardiovascular Medication
  • Statins

Description

  • Lipex is indicated as an adjunct to diet to reduce elevated total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B) and triglycerides levels in various diseases when response to diet and other non-pharmacological measures is inadequate.

Dosage Instructions

  • Adults: Usually 10 mg once daily; may be increased at intervals of at least 4 weeks to max. 80 mg once daily.

Pharmacological Action

  • Selective inhibitor of HMG-CoA reductase
  • Lowers plasma cholesterol and lipoprotein levels
  • Increases the number of hepatic LDL receptors

Absorption

  • Rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to 2 hours

Distribution

  • Mean volume of distribution of Atorvastatin is approximately 381 liters
  • Atorvastatin is 98% bound to plasma proteins

Metabolism

  • Extensively metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products

Excretion

  • Atorvastatin and its metabolites are eliminated primarily in bile following hepatic and/or extra-hepatic metabolism

Interaction

  • Increased risk of myopathy with concurrent administration of cyclosporine, fibric acid derivatives, niacin, erythromycin, azole antifungals
  • Altered plasma concentrations with antacid, colestipol, digoxin, erythromycin, oral contraceptives

Contraindications

  • Hypersensitivity to any component of this medication
  • Active liver disease or unexplained persistent elevations of serum transaminases

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Not known whether excreted in human milk
  • Maternal treatment may reduce fetal levels of mevalonate

Precautions & Warnings

  • Liver function tests should be performed before the initiation of treatment and periodically thereafter
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected.

Use in Special Populations

  • Plasma concentrations of Lipex are higher in healthy elderly subjects than in young adults
  • No clinically significant difference in LDL-C reduction with Lipex between men and women

Overdose Effects

  • Specific treatment is not available for atorvastatin overdose
  • Liver function tests should be performed and serum CK levels should be monitored

Therapeutic Class

  • Other Anti-anginal & Anti-ischaemic drugs
  • Statins

Storage Conditions

  • Keep in a dry place away from light and heat

Chemical Structure

  • Molecular Formula: C33H35FN2O5
  • Chemical Structure available

Commonly Asked Questions

  • What is Lipex 20 mg Tablet?
  • How should I take Lipex 20 mg Tablet?
  • What are the uses of Lipex 20 mg Tablet?
  • What are the Side Effects of Lipex 20 mg Tablet?
  • What are the instructions for storage and disposal of Lipex 20 mg Tablet?
  • Is Lipex 20 mg Tablet used for lowering cholesterol?
  • Will taking Lipex 20 mg Tablet increase my risk of diabetes?
  • For how long do I need to take Lipex 20 mg Tablet? Is it safe for long-term use?
  • Does Lipex 20 mg Tablet cause weight loss?
  • Can I stop taking Lipex 20 mg Tablet?
  • Does Lipex 20 mg Tablet cause memory loss?
  • Does Lipex 20 mg Tablet make you tired?
  • Can Lipex 20 mg Tablet be prescribed to children?
  • Is Lipex 20 mg Tablet a blood thinner?
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