Phendrin 10 mg/5 ml (Syrup)
100 ml bottle: ৳ 22.08
Medicine Details
| Category | Details |
|---|---|
| Generic | Diphenhydramine hydrochloride |
| Company | Salton pharmaceuticals ltd |
Title
- Phendrin Syrup
Categories
- Medicine
- Health & Wellness
Description
- Indicated for the treatment of allergic diseases such as hay fever, allergic rhinitis, urticaria, angioedema, atopic dermatitis, contact dermatitis, gastrointestinal allergy, pruritus, physical allergies, reaction to injection of contrast media, reaction to therapeutic preparation and allergic transfusion reactions; also postoperative nausea and vomiting and motion sickness. It is also used for the treatment of certain forms of parkinsonism and certain allergic conjunctivitis. Sometimes it may use as a night time sleep aid and for the short-term management of insomnia.
Dosage & Administration
- Adults: 25 mg to 50 mg 3 to 4 times daily
- Children (10 years or over): 25 mg 3 or 4 times daily or as directed by the physician
- Children under 2 years: 2.5 mL every 4 to 6 hours
- Children 2 to under 6 years: 5 mL every 4 to 6 hours
- Children 6 to 12 years: 10-20 mL every 4 to 6 hours
- Adults and children ≥12 years: 10-20 mL every 4 to 6 hours
- Adults and children over 12 years: 50 mg at bedtime
Indications
- Hay fever treatment
- Allergic rhinitis treatment
- Urticaria treatment
- Angioedema treatment
- Atopic dermatitis treatment
- Contact dermatitis treatment
- Gastrointestinal allergy treatment
- Pruritus treatment
- Postoperative nausea and vomiting treatment
- Motion sickness treatment
- Parkinsonism treatment
- Allergic conjunctivitis treatment
- Night time sleep aid
- Short-term management of insomnia
Pharmacology
- Anti-histaminic properties
- Anti-emetic properties
- Anti-vertigo properties
- Sedative and hypnotic properties
- Action by blocking spasmogenic and congestive effects of histamine by competing with histamine for H1 receptor sites on effector cells
Interaction
- Interaction with antidepressants
- Interaction with tricyclic and monoamine oxidase inhibitor types
- Prolonging and intensifying anticholinergic effects of antihistamines by MAO inhibitors
- Increased CNS effect by alcohol and other CNS depressant drugs
Contraindications
- Contraindicated for premature or newborn infants
- Hypersensitivity to any component of the drug
- Asthma attack
- Narrow angle glaucoma
- Prostatic hypertrophy
- Stenosing peptic ulcer
- Pyloroduodenal obstructions
- Bladder neck obstruction
- Patients receiving antidepressant therapy
Side Effects
- Drowsiness
- Dizziness
- Dryness of mouth
- Nausea
- Vomiting
- Vertigo
- Palpitation
- Blurring of vision
- Headache
- Restlessness
- Insomnia
- Thickening of bronchial secretions
- Allergic reactions
- Diarrhoea
- Excitation
Pregnancy & Lactation
- Safety for use in pregnancy and lactation has not been established. Its use therefore in such patients should involve consideration of expected benefits and possible risks.
Precautions & Warnings
- Patients should be cautioned not to operate vehicles or hazardous machinery until their response to the drug has been determined.
Overdose Effects
- Varied reactions from central nervous system depression to stimulation
- Atropine-like signs and symptoms such as dryness of mouth, fixed and dilated pupils, flushing and gastrointestinal symptoms
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Do not store above 30°C temperature
- Keep away from light and wet place
- Keep out of reach of children