Xyril 10 mg (Tablet)
Unit Price: ৳ 1.50 (10 x 20: ৳ 300.00)
Strip Price: ৳ 30.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Hydroxyzine hydrochloride |
| Company | Opsonin pharma ltd |
| Also available as |
Title and Categories
- Xyril Hydrochloride
- Sedating Anti-histamine
Dimensions
- N/A
Color Options
- N/A
Functions
- Symptomatic relief of anxiety and tension associated with psychoneurosis
- Management of pruritus due to allergic conditions
- Sedative when used as premedication and following general anesthesia
Materials
- Hydroxyzine Hydrochloride
Technical Specifications
- Anxiolytic antihistamine of the piperazine class
- H1 receptor antagonist
- Not a cortical depressant
- Rapidly absorbed from the gastrointestinal tract
Design Elements
- N/A
Usability Features
- Potentiates Meperidine and barbiturates
- Not known to interfere with the action of digitalis
- Contraindicated in patients with known hypersensitivity to Hydroxyzine or any of its ingredients
- Should be used with caution in conjunction with central nervous system depressants
Dosage and Administration
- Adults: 50-100 mg 4 times daily for symptomatic relief of anxiety and tension
- Children (>6 years): 50-100 mg (5-10 teaspoonfuls) daily in divided doses
- Children (<6 years): 50 mg (5 teaspoonfuls) daily in divided doses for symptomatic relief of anxiety and tension
- Adults: 25 mg 3 to 4 times daily for pruritus due to allergic conditions
- Children (6 years): 50-100 mg (5-10 teaspoonfuls) daily in divided doses
- Children (<6 years): 50 mg (5 teaspoonfuls) daily in divided doses for pruritus due to allergic conditions
- Adults: 50-100 mg as a sedative (premedication and following general anesthesia)
- Children: 0.6 mg/kg of body weight as a sedative (premedication and following general anesthesia)
Interaction
- Potentiates Meperidine and barbiturates
- Not affected by Atropine and other belladonna alkaloids
- Does not interfere with the action of digitalis
- Should be avoided with monoamine oxidase inhibitors
Contraindications
- Known hypersensitivity to Hydroxyzine or any of its ingredients
Side Effects
- Drowsiness
- Headache
- Psychomotor impairment
- Antimuscarinic effects like urinary retention, dry mouth, blurred vision, gastrointestinal disturbances
- Rare side-effects such as hypotension, palpitation, arrhythmias, extrapyramidal effects, dizziness, confusion, depression, sleep disturbances, tremor, convulsions, hypersensitivity reactions, blood disorders, liver dysfunction, angle-closure glaucoma
Pregnancy & Lactation
- Contraindicated in early pregnancy
- Unknown excretion in human milk, caution advised for nursing mothers
Precautions & Warnings
- Potentiating action with central nervous system depressants such as narcotics, non-narcotic analgesics, and barbiturates
- Patients should be warned of potential drowsiness and cautioned against driving or operating machinery
- Simultaneous use of other CNS depressant drugs should be avoided
- Reduced dosage recommended in renal impairment and elderly patients
Use in Special Populations
- Half of normal dose recommended in renal impairment
- Start with half the recommended dose in the elderly due to prolonged action
Overdose Effects
- Manifestations include hypersedation
- Vomiting induction and gastric lavage recommended
- Supportive care and close observation indicated
- Hypotension control with intravenous fluids and specific medications
- No specific antidote available
- Hemodialysis may be indicated in certain cases
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Store in a cool & dry place
- Protect from light
- Keep out of the reach of children