Acitrin 10 mg (Tablet)

Unit Price: ৳ 3.01 (10 x 10: ৳ 301.00)
Strip Price: ৳ 30.10

Medicine Details

Indications

  • Relief of symptoms associated with seasonal & perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen induced asthma

Pharmacology

  • H1 receptor antagonist
  • No significant anticholinergic and antiserotonic effects
  • Inhibits histamine-mediated early phase of allergic reaction
  • Reduces migration of inflammatory cells and release of mediators in late phase
  • Peak plasma concentrations of 257 mcg/L within one hour of administration
  • Plasma half-life of approximately 11 hours

Dosage & Administration

  • Dosage form: tablet, teaspoonfuls, injectable
  • Dosage for adults, children 6 years and older, children 2-6 years, children 6 months to 2 years, adults and adolescents 12 years of age and older, children 6 to 11 years of age, children 6 months to 5 years of age
  • Recommended dosage for intravenous injection
  • Not recommended in pediatric patients less than 6 years of age with impaired renal or hepatic function

Interaction

  • No clinically significant drug interactions with specific medications

Contraindications

  • Contraindicated in patients with history of hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Most common side effect is somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • No adequate and well-controlled studies in pregnant women
  • Drug excreted in human milk
  • Caution advised for nursing women

Precautions & Warnings

  • Caution advised when driving or operating heavy machinery

Use in Special Populations

  • Reduced clearance in patients with hepatic or renal insufficiency
  • Safety demonstrated in pediatric patients aged 6 months to 5 years
  • Reduced clearance in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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