Acitrin 5 mg/5 ml (Syrup)
60 ml bottle: ৳ 30.09
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Aci limited |
| Also available as |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
- Treatment of allergen induced asthma
Pharmacology
- Cetirizine Hydrochloride is a potent H1 receptor antagonist
- Inhibits histamine-mediated allergic reactions
- Reduces migration of inflammatory cells
- Does not cause significant drowsiness or behavioral changes
- Peak plasma concentrations of 257 mcg/L within one hour of administration
- Plasma half-life is approximately 11 hours
- Renal clearance is 30 ml/minute
Dosage & Administration
- Adults and Children 6 years and older: 1 tablet or 2 teaspoonfuls daily
- Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
- Children 6 months to 2 years: 1/2 teaspoonful once daily
- Recommended dosage regimen for injectable form for different age groups
Interaction
- No clinically significant drug interactions with specific drugs
Contraindications
- Contraindicated in patients with hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- The most common side effect is somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category of Cetirizine Hydrochloride is B
- Drug excreted in human milk
- Caution in use during pregnancy and lactation
Precautions & Warnings
- Caution when driving or operating heavy machinery
Use in Special Populations
- Reduced clearance and increased half-life in patients with mild to moderate hepatic and renal impairment
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduced clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children