Acitrin 2.5 mg/ml (Pediatric Drops)
15 ml bottle: ৳ 25.08
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Aci limited |
| Also available as |
Indications
- seasonal allergic rhinitis relief
- perennial allergic rhinitis relief
- uncomplicated skin manifestations of chronic idiopathic urticaria treatment
- allergen induced asthma treatment
Pharmacology
- potent H1 receptor antagonist
- no significant anticholinergic effects
- no significant antiserotonic effects
- inhibition of histamine-mediated early phase of allergic reaction
- reduction of migration of inflammatory cells
- reduction of release of mediators associated with late phase of allergic reaction
- peak plasma concentrations of 257 mcg/L within one hour of administration
- peak blood levels of 0.3 micrograms/ml reached between thirty & sixty minutes
- plasma half-life of approximately 11 hours
- renal clearance of 30 ml/minute
- excretion half-life of approximately nine hours
Dosage & Administration
- adult dosage of 1 tablet or 2 teaspoonfuls daily
- children (6 years and older) dosage of 1 teaspoonful twice daily
- children (2-6 years) dosage of 1 teaspoonful once daily
- children (6 months to 2 years) dosage of 1/2 teaspoonful once daily
- injectable dosage form for intravenous administration
- recommended dosage regimen of once every 24 hours for treatment of acute urticaria
- intravenous injection dosage for adults and adolescents of 10 mg
- intravenous injection dosage for children 6 to 11 years of 5 mg or 10 mg
- intravenous injection dosage for children 6 months to 5 years of 2.5 mg
Interaction
No clinically significant drug interactions found with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin
Contraindications
Patients with a history of hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category of Cetirizine Hydrochloride is B
- no adequate and well-controlled studies in pregnant women
- caution to be exercised when administered to a nursing woman
Precautions & Warnings
Caution when driving a car or operating heavy machinery
Use in Special Populations
- reduced clearance in patients with mild to moderate hepatic and renal impairment
- safety demonstrated in pediatric patients aged 6 months to 5 years
- reduced clearance in elderly patients
Therapeutic Class
Sedating Anti-histamine
Storage Conditions
Keep in a dry place away from light and heat, keep out of reach of children