Antrin 10 mg (Tablet)
Unit Price: ৳ 2.50 (100's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Central pharmaceuticals ltd |
Indications
- Relief of symptoms associated with seasonal & perennial allergic rhinitis
- Treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
- Treatment of allergen induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic and antiserotonic effects
- Inhibits histamine-mediated early phase of allergic reaction
- Reduces migration of inflammatory cells and release of mediators
- Peak plasma concentration of 257 mcg/L within one hour of administration
- Plasma half-life of approximately 11 hours
Dosage & Administration
- Dosage form: Cetirizine oral and injectable
- Recommended dosage for adults and children of different age groups
- Recommended intravenous dosage for different age groups
- Not recommended in pediatric patients less than 6 years of age with impaired renal or hepatic function
Interaction
- No clinically significant drug interactions with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin
Contraindications
- Contraindicated in patients with a history of hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Most common side effect is somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category B
- No adequate and well-controlled studies in pregnant women
- Excreted in human milk
- Caution advised when administered to a nursing woman
Precautions & Warnings
- Caution advised when driving a car or operating heavy machinery
Use in Special Populations
- Caution in patients with hepatic or renal insufficiency
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduction in clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children