Asitrol 10 mg (Tablet)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Asiatic laboratories ltd |
Indications
- relief of symptoms associated with seasonal & perennial allergic rhinitis
- treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
- treatment of allergen induced asthma
Pharmacology
- potent H1 receptor antagonist
- no significant anticholinergic and antiserotonic effects
- inhibits histamine-mediated early phase of allergic reaction
- reduces migration of inflammatory cells
- reduces release of mediators associated with late phase of allergic reaction
- peak plasma concentrations of 257 mcg/L within one hour of administration for adults
- peak plasma concentrations of 980 mcg/L in children within one hour of administration
- plasma half-life of approximately 11 hours
- renal clearance of 30 ml/minute
- excretion half-life of approximately nine hours
Dosage & Administration
- 1 tablet or 2 teaspoonfuls daily for adults and children 6 years and older
- 1 teaspoonful once daily for children 2-6 years
- 1/2 teaspoonful once daily for children 6 months to 2 years
- once every 24 hours as needed for treatment of acute urticaria for adults and adolescents 12 years of age and older
- recommended dosage of 10 mg administered by intravenous injection for adults and adolescents 12 years of age and older
- recommended dosage of 5 mg or 10 mg depending on symptom severity administered by intravenous injection for children 6 to 11 years of age
- recommended dosage of 2.5 mg administered by intravenous injection for children 6 months to 5 years of age
Interaction
- no clinically significant drug interactions with Theophylline
- no clinically significant drug interactions with Azithromycin
- no clinically significant drug interactions with Pseudoephedrine
- no clinically significant drug interactions with Ketoconazole
- no clinically significant drug interactions with Erythromycin
Contraindications
- contraindicated in patients with a history of hypersensitivity to Cetirizine
- contraindicated in patients with a history of hypersensitivity to hydroxyzine
Side Effects
- somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category B
- caution should be exercised when administered to a nursing woman
Precautions & Warnings
- caution should be exercised when driving a car or operating heavy machinery
Use in Special Populations
- caution should be exercised in patients with mild to moderate hepatic and renal impairment
- safety demonstrated in pediatric patients aged 6 months to 5 years
- reduced clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- keep in a dry place away from light and heat
- keep out of the reach of children