B-Cef 10 mg (Tablet)

Unit Price: ৳ 2.50 (10 x 10: ৳ 250.00)
Strip Price: ৳ 25.00

Medicine Details

Category Details
Generic Cetirizine hydrochloride
Company Belsen pharmaceuticals ltd
Also available as

Indications

  • Relief of symptoms associated with seasonal & perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen induced asthma

Pharmacology

  • Potent H1 receptor antagonist
  • No significant anticholinergic and antiserotonic effects
  • Inhibition of histamine-mediated early phase of allergic reaction
  • Reduction of migration of inflammatory cells
  • Reduction of mediators associated with late phase of allergic reaction
  • Peak plasma concentrations of 257 mcg/L within one hour of administration

Dosage & Administration

  • Adults and Children 6 years and older: 1 tablet or 2 teaspoonfuls daily
  • Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
  • Children 6 months to 2 years: 1/2 teaspoonful once daily
  • Adults and adolescents 12 years of age and older: The recommended dosage is 10 mg administered by intravenous injection

Interaction

  • No clinically significant drug interactions with Theophylline
  • No clinically significant drug interactions with Azithromycin
  • No clinically significant drug interactions with Pseudoephedrine
  • No clinically significant drug interactions with Ketoconazole
  • No clinically significant drug interactions with Erythromycin

Contraindications

  • Patients with a history of hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Excreted in human milk
  • Caution should be exercised when administered to a nursing woman

Precautions & Warnings

  • Caution should be exercised when driving a car or operating heavy machinery

Use in Special Populations

  • Total body clearance of B-Cef is reduced and AUC and half-life increased in patients with mild to moderate hepatic and renal impairment
  • Plasma levels are unaffected by hemodialysis
  • The safety of B-Cef has been demonstrated in pediatric patients aged 6 months to 5 years
  • The clearance of B-Cef is reduced in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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