B-Cef 5 mg/5 ml (Syrup)

60 ml bottle: ৳ 20.00

Medicine Details

Indications

  • Relief of symptoms associated with seasonal & perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen induced asthma

Pharmacology

  • Potent H1 receptor antagonist
  • Does not cause significant anticholinergic and antiserotonic effects
  • Inhibits histamine-mediated early phase of allergic reaction
  • Reduces migration of inflammatory cells and release of mediators associated with late phase of allergic reaction
  • Plasma half-life of approximately 11 hours

Dosage & Administration

  • Adult dosage: 1 tablet or 2 teaspoonfuls daily
  • Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoonful twice daily
  • Injectable dosage: 5 mg, 10 mg, or 2.5 mg depending on age and severity of symptoms

Interaction

  • No clinically significant interactions with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin

Contraindications

  • Contraindicated in patients with hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Most common side effect is somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Use during pregnancy only if clearly needed
  • Cetirizine excreted in human milk, caution needed during nursing

Precautions & Warnings

  • Caution needed when driving or operating heavy machinery

Use in Special Populations

  • Reduced clearance and increased half-life in patients with hepatic or renal insufficiency
  • Demonstrated safety in pediatric patients aged 6 months to 5 years
  • Reduced clearance in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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