Cetrimax 10 mg (Tablet)
Unit Price: ৳ 2.50 (100's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Cetirizine hydrochloride |
| Company | Novus pharmaceuticals ltd |
Indications
- Relief of symptoms associated with seasonal allergic rhinitis
- Relief of symptoms associated with perennial allergic rhinitis
- Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
- Treatment of allergen-induced asthma
Pharmacology
- Potent H1 receptor antagonist
- No significant anticholinergic effects
- No significant antiserotonic effects
- Inhibits histamine-mediated early phase of allergic reaction
- Reduces migration of inflammatory cells
- Reduces release of mediators associated with late phase of allergic reaction
- Peak plasma concentrations achieved within one hour of administration
- Plasma half-life of approximately 11 hours
- Renal clearance of 30 ml/minute
- Excretion half-life of approximately nine hours
Dosage & Administration
- Dosage form: oral tablet
- Dosage form: oral teaspoonful
- Dosage form: injectable for intravenous administration
- Different dosage for adults and children
- Recommended dosage for different age groups
Interaction
- No clinically significant drug interactions with Theophylline
- No clinically significant drug interactions with Azithromycin
- No clinically significant drug interactions with Pseudoephedrine
- No clinically significant drug interactions with Ketoconazole
- No clinically significant drug interactions with Erythromycin
- No clinically significant drug interactions with other drugs
Contraindications
- Contraindicated in patients with history of hypersensitivity to Cetirizine
- Contraindicated in patients with history of hypersensitivity to hydroxyzine
Side Effects
- Most common side effect: somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category B
- No adequate and well-controlled studies in pregnant women
- Use during pregnancy only if clearly needed
- Cetirizine excreted in human milk
- Caution required when administered to a nursing woman
Precautions & Warnings
- Caution required when driving a car
- Caution required when operating heavy machinery
Use in Special Populations
- Reduced total body clearance in patients with mild to moderate hepatic impairment
- Reduced total body clearance in patients with mild to moderate renal impairment
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduced clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place
- Keep away from light
- Keep away from heat
- Keep out of the reach of children