Cetzin 10 mg (Tablet)

Unit Price: ৳ 3.00 (100's pack: ৳ 300.00)

Medicine Details

Category Details
Generic Cetirizine hydrochloride
Company Cosmic pharma ltd
Also available as

Indications

  • Relief of symptoms associated with seasonal & perennial allergic rhinitis
  • Treatment of uncomplicated skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen-induced asthma

Pharmacology

  • Potent H1 receptor antagonist
  • No significant anticholinergic and antiserotonic effects
  • Inhibits histamine-mediated early phase of allergic reaction
  • Reduces migration of inflammatory cells
  • Reduces release of mediators associated with late phase of allergic reaction
  • Peak plasma concentration of 257 mcg/L within one hour of administration
  • Plasma half-life approximately 11 hours

Dosage & Administration

  • Adult dosage: 1 tablet or 2 teaspoonfuls daily
  • Pediatric dosage: varies by age group
  • Single use injectable product for intravenous administration only
  • Dosage for adult, adolescent, and pediatric patients based on age and severity of symptoms

Interaction

  • No clinically significant drug interactions found with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin

Contraindications

  • Contraindicated in patients with history of hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Most common side effect is somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Use during pregnancy only if clearly needed
  • Excreted in human milk, caution advised when administered to nursing women

Precautions & Warnings

  • Caution advised when driving a car or operating heavy machinery

Use in Special Populations

  • Reduced clearance in patients with mild to moderate hepatic and renal impairment
  • Safety demonstrated in pediatric patients aged 6 months to 5 years
  • Clearance reduced in elderly patients

Therapeutic Class

  • Sedating Antihistamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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