Lipiles 10 mg (Tablet)
Unit Price: ৳ 10.00 (2 x 10: ৳ 200.00)
Strip Price: ৳ 100.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Pharmasia limited |
| Also available as |
Title
- Lipiles 10 mg Tablet
Category
- Medication
- Health & Wellness
Description
- Lipid-lowering medication used to reduce cholesterol levels and prevent cardiovascular events
DosageForm
- Tablet
DosageStrength
- 10 mg
Indications
- Reduction of total cholesterol
- Lowering LDL cholesterol
- Reducing triglycerides levels
- Prevention of cardiovascular events
PharmacologicalAction
- Inhibition of HMG-CoA reductase
- Lowering plasma cholesterol and lipoprotein levels
- Increasing hepatic LDL receptors
Absorption
- Rapidly absorbed after oral administration
- Maximum plasma concentrations occur within 1 to 2 hours
Metabolism
- Extensively metabolized to ortho- and parahydroxylated derivatives
- Metabolism by cytochrome P450 3A4
- Ortho-hydroxy metabolite undergoes glucuronidation
Excretion
- Eliminated primarily in bile
- Mean plasma elimination half-life approximately 14 hours
Interaction
- Risk of myopathy with concurrent administration of certain drugs
- Plasma concentration interactions with antacid, colestipol, digoxin, erythromycin, oral contraceptives, and warfarin
Contraindications
- Hypersensitivity to any component
- Active liver disease
- History of serious adverse reaction to HMG-CoA reductase inhibitors
SideEffects
- Constipation
- Flatulence
- Dyspepsia
- Headache
- Back pain
- Rash
- Asthenia
- Arthralgia
- Myalgia
- Infection
- Abdominal pain
PregnancyAndLactation
- Contraindicated during pregnancy
- Not recommended during breastfeeding
Precautions
- Monitoring of liver function tests
- Caution in patients with alcohol consumption or history of liver disease
- Discontinuation if markedly elevated CPK levels or myopathy occurs
SpecialPopulations
- Elevated plasma concentrations in elderly subjects
- No clinically significant difference in LDL-C reduction between men and women
- No dose adjustment in renal dysfunction necessary
- Markedly increased plasma concentrations in chronic alcoholic liver disease
OverdoseEffects
- Specific treatment not available
- Symptomatic treatment and supportive measures recommended
- Monitoring of liver function tests and serum CK levels
TherapeuticClass
- Other Anti-anginal & Anti-ischaemic drugs
- Statins
StorageConditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children
ChemicalStructure
- Molecular Formula: C33H35FN2O5
- Chemical Structure available
CommonQuestions
- Description of the medication
- Dosage instructions
- Uses of the medication
- Side effects
- Storage and disposal instructions
- Safety for long-term use
- Effect on diabetes risk
- Effect on weight loss
- Recommendation not to stop without informing the doctor
- Effect on memory loss
- Possibility of tiredness
- Prescription to children
- Blood thinning clarification
- Quick Tips for usage
OtherInformation
- Elevated cholesterol levels associated with diabetes mellitus or renal transplantation
- Potential impact on fetal levels of mevalonate in pregnant women
- Plasma concentrations of atorvastatin and its metabolites in rats similar to those in milk
- Influences of hemodialysis and hepatic insufficiency on plasma concentrations
- No clinically significant effect on prothrombin time in patients on chronic warfarin treatment