Histacet 10 mg (Tablet)

Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)

Medicine Details

Indications

  • Relief of seasonal and perennial allergic rhinitis symptoms
  • Treatment of skin manifestations of chronic idiopathic urticaria
  • Treatment of allergen-induced asthma

Pharmacology

  • H1 receptor antagonist
  • No significant anticholinergic or antiserotonic effects
  • Inhibits histamine-mediated allergic reactions
  • Reduces migration of inflammatory cells
  • Reduces release of mediators
  • Peak plasma concentration of 257 mcg/L within one hour of administration
  • Plasma half-life of approximately 11 hours
  • Consistent absorption from one subject to the next

Dosage & Administration

  • Adult dosage of 10mg daily
  • Children dosage based on age and weight
  • Single use injectable product for intravenous administration only
  • Different dosage for adults, adolescents, and children based on age and symptom severity

Interaction

  • No clinically significant drug interactions with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin

Contraindications

  • History of hypersensitivity to Cetirizine or hydroxyzine

Side Effects

  • Somnolence

Pregnancy & Lactation

  • US FDA Pregnancy Category B
  • Excreted in human milk
  • Caution during pregnancy and nursing

Precautions & Warnings

  • Caution when driving or operating heavy machinery

Use in Special Populations

  • Reduced clearance in patients with hepatic or renal insufficiency
  • Safety demonstrated in pediatric patients aged 6 months to 5 years
  • Reduced clearance in elderly patients

Therapeutic Class

  • Sedating Anti-histamine

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

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