Histacet 10 mg (Tablet)
Unit Price: ৳ 2.00 (100's pack: ৳ 200.00)
Medicine Details
Category | Details |
---|---|
Generic | Cetirizine hydrochloride |
Company | Medimet pharmaceuticals ltd |
Also available as |
Indications
- Relief of seasonal and perennial allergic rhinitis symptoms
- Treatment of skin manifestations of chronic idiopathic urticaria
- Treatment of allergen-induced asthma
Pharmacology
- H1 receptor antagonist
- No significant anticholinergic or antiserotonic effects
- Inhibits histamine-mediated allergic reactions
- Reduces migration of inflammatory cells
- Reduces release of mediators
- Peak plasma concentration of 257 mcg/L within one hour of administration
- Plasma half-life of approximately 11 hours
- Consistent absorption from one subject to the next
Dosage & Administration
- Adult dosage of 10mg daily
- Children dosage based on age and weight
- Single use injectable product for intravenous administration only
- Different dosage for adults, adolescents, and children based on age and symptom severity
Interaction
- No clinically significant drug interactions with Theophylline, Azithromycin, Pseudoephedrine, Ketoconazole, or Erythromycin
Contraindications
- History of hypersensitivity to Cetirizine or hydroxyzine
Side Effects
- Somnolence
Pregnancy & Lactation
- US FDA Pregnancy Category B
- Excreted in human milk
- Caution during pregnancy and nursing
Precautions & Warnings
- Caution when driving or operating heavy machinery
Use in Special Populations
- Reduced clearance in patients with hepatic or renal insufficiency
- Safety demonstrated in pediatric patients aged 6 months to 5 years
- Reduced clearance in elderly patients
Therapeutic Class
- Sedating Anti-histamine
Storage Conditions
- Keep in a dry place away from light and heat
- Keep out of the reach of children